PLXNA2
-
Official Full Name
plexin A2 -
Overview
This gene encodes a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding during nervous system development. A subset of semaphorins are recognized by plexin-A/neuropilin transmembrane receptor complexes, triggering a cellular signal transduction cascade that leads to axon repulsion. This plexin-A family member is thought to transduce signals from semaphorin-3A and -3C. [provided by RefSeq, Jul 2008] -
Synonyms
PLXNA2;plexin A2;OCT;PLXN2;plexin-A2;plexin 2;semaphorin receptor OCT;transmembrane protein OCT
Recombinant Proteins
- Human
- Mouse
- Wheat Germ
- CHO
- Mammalian Cells
- Human
- HEK293
- E.coli
- Yeast
- Non
- His
- N-SUMO & C-His
- GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PLXNA2-30876TH | Recombinant Human PLXNA2 | Wheat Germ | Human | Non | 165 amino acids | |
| Plxna2-441M |
Active Recombinant Mouse Plxna2, His-tagged
|
CHO | Mouse | His | 25-1227 a.a. |
|
| PLXNA2-12999M | Recombinant Mouse PLXNA2 Protein | Mammalian Cells | Mouse | His |
|
|
| PLXNA2-312H | Recombinant Human Plexin A2 | Human | Non |
|
||
| PLXNA2-001H | Recombinant Human plexin A2 Protein, His-tagged | HEK293 | Human | His | 35-1237 aa |
|
| PLXNA2-20H | Recombinant Human PLXNA2 protein(Thr861- Val1220), His-tagged | E.coli | Human | His | Thr861- Val1220 |
|
| PLXNA2-21H | Recombinant Human PLXNA2 protein(Thr861- Val1220), SUMO &His-tagged | E.coli | Human | N-SUMO & C-His | Thr861- Val1220 |
|
| PLXNA2-22H | Recombinant Human plexin A2 Protein, GST-tagged | HEK293 | Human | GST | 1743-1894aa |
|
| PLXNA2-23H | Recombinant Human plexin A2 Protein, GST-tagged | Yeast | Human | GST | 1743-1894aa |
|
| PLXNA2-6865M | Recombinant Mouse PLXNA2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
|
| PLXNA2-6865M-B | Recombinant Mouse PLXNA2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
Involved Pathway
PLXNA2 involved in several pathways and played different roles in them. We selected most pathways PLXNA2 participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLXNA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Axon guidance | ARPC2,ARHGEF28,TRPC4,ITGB1B.1,PAK1,CSNK2B,SEMA5A,SLIT3,PPP3R1,ARPC3 |
Protein Function
PLXNA2 has several biochemical functions, for example, semaphorin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PLXNA2 itself. We selected most functions PLXNA2 had, and list some proteins which have the same functions with PLXNA2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| semaphorin receptor activity | PLXNA3,NRP1B,NRP1,PLXNB2A,PLXNA1B,PLXNB2B,NRP2A,NRP1A,PLXND1,PLXNA1 |
Interacting Protein
PLXNA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLXNA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PLXNA2.
Resources
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References
- Ji, JD; Park-Min, KH; et al. Expression and function of semaphorin 3A and its receptors in human monocyte-derived macrophages. HUMAN IMMUNOLOGY 70:211-217(2009).
- Suto, F; Murakami, Y; et al. Identification and characterization of a novel mouse plexin, plexin-A4. MECHANISMS OF DEVELOPMENT 120:385-396(2003).
