PLA2G15
-
Official Full Name
phospholipase A2, group XV -
Overview
Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The;protein encoded by this gene hydrolyzes lysophosphatidylcholine to glycerophosphorylcholine and a free fatty acid.;This enzyme is present in the plasma and thought to be associated with high-density lipoprotein. A later paper;contradicts the function of this gene. It demonstrates that this gene encodes a lysosomal enzyme instead of a;lysophospholipase and has both calcium-independent phospholipase A2 and transacylase activities. -
Synonyms
PLA2G15;phospholipase A2, group XV;LYPLA3, lysophospholipase 3 (lysosomal phospholipase A2);group XV phospholipase A2;GXVPLA2;LLPL;1 O acylceramide synthase;ACS;DKFZp564A0122;LCAT like lysophospholipase;LPLA2;Lysophospholipase 3 (lysosomal phospholipase A2);Lysophospholipase 3;Lysosomal phospholipase A2;OTTHUMP00000174859;UNQ341/PRO540;1-O-acylceramide synthase;LCAT-like lysophospholipase;LYPLA3
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Rat
- Dog
- Chinese hamster
- E.coli
- Mammalian Cells
- HEK293
- Insect Cells
- Yeast
- CHO
- Wheat Germ
- In Vitro Cell Free System
- GST
- His
- Non
- His&Myc
- Myc&DDK
- His&Fc&Avi
- Flag
- N-His&C-Myc
Involved Pathway
PLA2G15 involved in several pathways and played different roles in them. We selected most pathways PLA2G15 participated on our site, such as Glycerophospholipid metabolism,Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLA2G15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Lysosome | ATP6AP1B,ATP6AP1,AP1G2,MANBA,ABCB9,ATP6V0CB,AGA,DNASE2A,AP4B1,SUMF1 |
| Glycerophospholipid metabolism | LPCAT4,LPIN3,AGPAT1,DGKB,PTDSS2,PPAP2D,PHYKPL,PLA2G2E,PPAP2CB,PLD4 |
Protein Function
PLA2G15 has several biochemical functions, for example, O-acyltransferase activity,calcium-independent phospholipase A2 activity,lysophospholipase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PLA2G15 itself. We selected most functions PLA2G15 had, and list some proteins which have the same functions with PLA2G15. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| O-acyltransferase activity | MBOAT7,HHAT,DGAT1B,DGAT2L6,MBOAT1,DGAT1A,ACNAT2,Acnat1,LPCAT3,MBOAT4 |
| calcium-independent phospholipase A2 activity | PNPLA8,PLA2G4C,PLA2G7 |
| phospholipid binding | BAD,DAPP1,APOC3,SYTL4,WDFY4,PON1,APOH,PACSIN1,PREX1,APOA2 |
| lysophospholipase activity | PNPLA6,PLB1,PNPLA7,Cel,MGLL,LYPLA1,PLA2G4F,PLA2G4B,PNPLA7A,LGALS13 |
Interacting Protein
PLA2G15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLA2G15 here. Most of them are supplied by our site. Hope this information will be useful for your research of PLA2G15.
IMMT;cona_canen
Resources
Related Services
Related Products
References
