NKX3-2
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Official Full Name
NK3 homeobox 2 -
Synonyms
NKX3-2;NK3 homeobox 2;homeobox protein Nkx-3.2;Bagpipe homeobox 1;Bagpipe homeobox homolog 1;Bagpipe homeobox protein homolog 1;BAPX 1;Homeobox protein NK-3 homolog B;Homeobox protein Nkx 3.2;MGC138171;NKX3 2;NKX3.2;NKX32_HUMAN;NKX3B;OTTHUMP00000115816;SMMD;homeodomain protein Nkx-3.2;bagpipe homeobox gene 1 homolog;Bapx1;Nkx-3.2
Recombinant Proteins
- Human
- Rhesus macaque
- Chicken
- Mouse
- Wheat Germ
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- Myc
- SUMO
- Avi
- Fc
- Non
- DDK
Involved Pathway
NKX3-2 involved in several pathways and played different roles in them. We selected most pathways NKX3-2 participated on our site, such as Endochondral Ossification, which may be useful for your reference. Also, other proteins which involved in the same pathway with NKX3-2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Endochondral Ossification | IFT88,SOX6,SOX9A,COL10A1,RUNX2A,DDR2,MGP,FRZB,ADAMTS1,SERPINH1 |
Protein Function
NKX3-2 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding,transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NKX3-2 itself. We selected most functions NKX3-2 had, and list some proteins which have the same functions with NKX3-2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | NFATC4,HINFP,PGR,HAND1,GLI2,OTX1,NFATC2,SMAD2,FOS,PBX1 |
| transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding | TFAP2C,FOXO1,YY1,ZFP536,BACH1,NR2E1,HAND1,TGIF1,HES1,ESRRA |
Interacting Protein
NKX3-2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NKX3-2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NKX3-2.
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References
- Schlange, T; Schnipkoweit, I; et al. Chick CFC controls Lefty1 expression in the embryonic midline and nodal expression in the lateral plate. DEVELOPMENTAL BIOLOGY 234:376-389(2001).
