NKX3-2
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Official Full Name
NK3 homeobox 2 -
Synonyms
NKX3-2;NK3 homeobox 2;homeobox protein Nkx-3.2;Bagpipe homeobox 1;Bagpipe homeobox homolog 1;Bagpipe homeobox protein homolog 1;BAPX 1;Homeobox protein NK-3 homolog B;Homeobox protein Nkx 3.2;MGC138171;NKX3 2;NKX3.2;NKX32_HUMAN;NKX3B;OTTHUMP00000115816;SMMD;homeodomain protein Nkx-3.2;bagpipe homeobox gene 1 homolog;Bapx1;Nkx-3.2
Recombinant Proteins
- Human
- Rhesus macaque
- Chicken
- Mouse
- Wheat Germ
- E.coli
- Mammalian Cells
- HEK293
- GST
- His&Myc
- His
- His&SUMO
- His&Fc&Avi
- Non
- Myc&DDK
Involved Pathway
NKX3-2 involved in several pathways and played different roles in them. We selected most pathways NKX3-2 participated on our site, such as Endochondral Ossification, which may be useful for your reference. Also, other proteins which involved in the same pathway with NKX3-2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Endochondral Ossification | COL10A1,COL10A1A,ADAMTS1,KIF3A,NKX3.2,RUNX2A,RUNX3,SOX9A,DDR2,FRZB |
Protein Function
NKX3-2 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding,transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NKX3-2 itself. We selected most functions NKX3-2 had, and list some proteins which have the same functions with NKX3-2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | RBPJA,ATOH1,JUNBA,NR2C1,BATF,DDIT3,NACC2,ZNF718,MEF2A,SIX4 |
| transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding | PITX2,ZKSCAN3,PROX1A,HES1,NFE2L3,POU4F2,HHEX,NACC2,GZF1,MZF1 |
Interacting Protein
NKX3-2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NKX3-2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NKX3-2.
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References
- Schlange, T; Schnipkoweit, I; et al. Chick CFC controls Lefty1 expression in the embryonic midline and nodal expression in the lateral plate. DEVELOPMENTAL BIOLOGY 234:376-389(2001).
