NEK6

  • Official Full Name

    NIMA (never in mitosis gene a)-related expressed kinase 6
  • Overview

    The Aspergillus nidulans never in mitosis A (NIMA) gene encodes a serine/threonine kinase that controls initiation of mitosis. NIMA-related kinases (NEKs) are a group of protein kinases that are homologous to NIMA. Evidence suggests that NEKs perform f
  • Synonyms

    NEK6;NIMA (never in mitosis gene a)-related expressed kinase 6;serine/threonine-protein kinase Nek6;Highly similar to cell cycle protein kinase CDC5/MSD2;NEK6_HUMAN;Never in mitosis A-related kinase 6;NIMA (Never In Mitosis Gene A) Related Kinase 6;NimA related protein kinase 6;NimA-related protein kinase 6;Protein kinase SID6 1512;Protein kinase SID6-1512;Putative serine threonine protein kinase;Serine/threonine protein kinase Nek6;SID6 1512;SID61512;NIMA-related expressed kinase 6;1300007C09Rik

Recombinant Proteins

  • Chicken
  • Human
  • Mouse
  • Mammalian Cells
  • Sf9 Cells
  • E.coli
  • HEK293
  • Insect Cells
  • Sf21 Cells
  • His
  • Non
  • GST
  • DDK&Myc
Cat.# Product name Source (Host) Species Tag Protein Length Price
NEK6-1905C Recombinant Chicken NEK6 Mammalian Cells Chicken His
NEK6-28258TH Recombinant Human NEK6, His-tagged Human His Full L.
NEK6-29622TH Recombinant Human NEK6 Human Non Full L.
NEK6-370H Recombinant Human NEK6, GST-tagged, Active Sf9 Cells Human GST
NEK6-559H Recombinant Human NEK6, His-tagged Sf9 Cells Human His
NEK6-662H Recombinant Human NEK6, Active E.coli Human Non
NEK6-3877HCL Recombinant Human NEK6 293 Cell Lysate HEK293 Human Non
NEK6-0907H Recombinant Human NEK6 Protein (A2-T313), Tag Free Insect Cells Human Non A2-T313
NEK6-0908H Recombinant Human NEK6 Protein (A2-T313), GST tagged Insect Cells Human GST A2-T313
NEK6-2010HF Active Recombinant Full Length Human NEK6 Protein, GST-tagged Sf21 Cells Human GST Full L. 1-313
NEK6-3564H Recombinant Human NEK6 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
NEK6-4335H Recombinant Human NEK6 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
Nek6-4368M Recombinant Mouse Nek6 Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc

    Involved Pathway

    NEK6 involved in several pathways and played different roles in them. We selected most pathways NEK6 participated on our site, such as Activation of NIMA Kinases NEK9, NEK6, NEK7,Cell Cycle,Cell Cycle, Mitotic, which may be useful for your reference. Also, other proteins which involved in the same pathway with NEK6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Activation of NIMA Kinases NEK9, NEK6, NEK7 NEK7,NEK9
    Nuclear Pore Complex (NPC) Disassembly NEK7,NEK9
    M Phase NEK9,CTDNEP1,VRK2,KIF2B,NIPBLA,MLF1IP,NEK7,NCAPG,CENPP,RCC2
    Mitotic Prophase NEK7,SETA,VRK1,SET,SMC2,CNEP1R1,NCAPG2,ENSAA,SETB,ARPP19A
    Cell Cycle, Mitotic CENPE,HIST3H2BB,LIN37,POLD3,H3F3D,PCM1,NDEL1,E2F3,CEP57,ESCO2
    Nuclear Envelope Breakdown CTDNEP1,CNEP1R1,NEK7,CTDNEP1B,NEK9,DULLARD,CTDNEP1A,TMEM188
    Cell cycle CDKN1BB,CEP164,CCNA1,CSNK2A1,CTDNEP1A,CCNB2,PDS5B,CENPI,SMAD3B,STAG1

    Protein Function

    NEK6 has several biochemical functions, for example, ATP binding,kinesin binding,magnesium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NEK6 itself. We selected most functions NEK6 had, and list some proteins which have the same functions with NEK6. You can find most of the proteins on our site.

    Function Related Protein
    kinesin binding ARPC2,KIFAP3A,JAKMIP1,MAPK8IP3,ARHGEF10,SNCA,PPIAL4A,NUP62,PLEKHM2,CD36
    protein kinase binding EMP2,FER,RB1CC1,BCAR1,VRK2,CAMK2N1,PDGFRB,PTPRK,DVL1,TENC1
    ATP binding MAPK14B,CHD1,SUPV3L1,PTK2BB,EPHA4B,HIPK1,SYN2B,DHX35,KDRL,YES1
    protein serine/threonine kinase activity MAP2K1,BMPR1B,TGFBR1B,STK32A,DSTYK,TRIOA,CDC42BPA,BUB1B,PRKCBA,CSNK1DA
    signal transducer activity GNAS,ILK,GNA11,DRD4-RS,PTK2AA,NPY8AR,CCR9A,GNA14,AXIN1,V2RX1
    magnesium ion binding PAPOLA,DUT,ERN1,PKM2,PRPS2,NT5C1AA,DYRK3,ATP11A,ATP11C,STK3
    protein binding IK,CRYBB1,CCDC117,MRPL1,CD24,HDDC2,CHUK,PRF1,GLI2,UNC119B

    Interacting Protein

    NEK6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NEK6 here. Most of them are supplied by our site. Hope this information will be useful for your research of NEK6.

    NECAB2;TRIM27;TCF4;TRIM23;XIAP;TNK2;AES

    Resources

    References

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