NBL1
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Official Full Name
neuroblastoma, suppression of tumorigenicity 1 -
Overview
This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins a -
Synonyms
NBL1;neuroblastoma, suppression of tumorigenicity 1;neuroblastoma suppressor of tumorigenicity 1;D1S1733E;DAN;DAN domain family member 1;DAND 1;DAND1;Differential screening selected gene aberrant in neuroblastoma;MGC8972;NB;NBL 1;Neuroblastoma candidate region suppression of tumorigenicity 1;Neuroblastoma suppression of tumorigenicity 1;NO 3;NO3;Zinc finger protein DAN;N03;OTTMUSP00000010476;Dana;D4H1S1733E
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Rat
- Chicken
- HEK293
- Mammalian cells
- Mammalian Cell
- E.coli
- Human Cell
- His
- Fc
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
NBL1 involved in several pathways and played different roles in them. We selected most pathways NBL1 participated on our site, such as TGF-beta signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with NBL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| TGF-beta signaling pathway | ACVR1L,TGFB1,LTBP1,BMP8B,LFT2,INHBA,LFT1,INHBC,SMAD7B,TFDP1 |
Protein Function
NBL1 has several biochemical functions, for example, BMP binding,morphogen activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NBL1 itself. We selected most functions NBL1 had, and list some proteins which have the same functions with NBL1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | HIST1H2AM,PRKCD,MT1G,UNKL,STX7,ZNF317,GBP1,MCCC1,TRPV5,CD70 |
| BMP binding | BMPR2,TCAP,CER1,GREM2,GDF5,HFE2,GREM1 |
| protein homodimerization activity | TKT,TRIM9,HLA-G,BCL2A1,USH2A,CADM1A,BMPR1A,FLNA,PRDX4,TENM2 |
| morphogen activity | GREM1,NODAL,Shh,CER1,DAND5 |
Interacting Protein
NBL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NBL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NBL1.
NCS1;ZMIZ2;UBQLN1;UBQLN1
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