MOCS3
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Official Full Name
molybdenum cofactor synthesis 3 -
Overview
Molybdenum cofactor (MoCo) is necessary for the function of all molybdoenzymes. One of the enzymes required for the biosynthesis of MoCo is molybdopterin synthase (MPT synthase). The protein encoded by this gene adenylates and activates MPT synthase. This gene contains no introns. A pseudogene of this gene is present on chromosome 14. -
Synonyms
MOCS3;molybdenum cofactor synthesis 3;adenylyltransferase and sulfurtransferase MOCS3;dJ914P20.3;UBA4;ubiquitin activating enzyme E1 homolog (yeast);ubiquitin like modifier activating enzyme 4;MGC9252;MOCS 3;Molybdenum cofactor synthesis protein 3;Molybdopterin synthase sulfurylase;MPT synthase sulfurylase;UBA 4;UBA4ubiquitin activating enzyme E1 homolog;OTTHUMP00000031284;ubiquitin-like modifier activating enzyme 4;UBA4, ubiquitin-activating enzyme E1 homolog
Recombinant Proteins
- Zebrafish
- Human
- Mouse
- Mammalian Cells
- HEK293
- E.Coli/Yeast
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- Myc&DDK
- GST
- His&Fc&Avi
Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
MOCS3-10478Z | Recombinant Zebrafish MOCS3 | Mammalian Cells | Zebrafish | His | ||
MOCS3-143H | Recombinant Human MOCS3, His-tagged | HEK293 | Human | His | 1-460 a.a. | |
Mocs3-3194M | Recombinant Mouse Mocs3, His-tagged | E.Coli/Yeast | Mouse | His | 460 | |
MOCS3-9950M | Recombinant Mouse MOCS3 Protein | Mammalian Cells | Mouse | His | ||
MOCS3-4259HCL | Recombinant Human MOCS3 293 Cell Lysate | HEK293 | Human | Non | ||
Mocs3-4110M | Recombinant Mouse Mocs3 Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK | ||
MOCS3-5465H | Recombinant Human MOCS3 Protein, GST-tagged | Wheat Germ | Human | GST | ||
MOCS3-5624M | Recombinant Mouse MOCS3 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi | ||
MOCS3-5624M-B | Recombinant Mouse MOCS3 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse | |||
MOCS3-585H | Recombinant Human MOCS3 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK | ||
MOCS3-6301HF | Recombinant Full Length Human MOCS3 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 460 amino acids |
Involved Pathway
MOCS3 involved in several pathways and played different roles in them. We selected most pathways MOCS3 participated on our site, such as Sulfur relay system, which may be useful for your reference. Also, other proteins which involved in the same pathway with MOCS3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Sulfur relay system | LBH,MOCS1,TST,NFS1,URM1,CTU2,TRMU,CTU1,MPST,MOCS2 |
Protein Function
MOCS3 has several biochemical functions, for example, ATP binding,URM1 activating enzyme activity,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MOCS3 itself. We selected most functions MOCS3 had, and list some proteins which have the same functions with MOCS3. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
ATP binding | ROCK2B,PDPK1,TRIB3,EHD2,ABCB9,CASK,UBA2,SGK3,HSPA7,CDK14 |
nucleotidyltransferase activity | POLR2B,CCDC111,CTU2,TAMM41,OASL2,UAP1L1,GDPGP1,POLE2,PRIM2,CMASB |
protein adenylyltransferase activity | FICD |
metal ion binding | ZDHHC15A,ZFP879,EFCAB5,CYBRD1,TSSK5,ZNF488,FDPS,ZFP474,ZFP42,MMP1A |
thiosulfate sulfurtransferase activity | MPST,TST |
sulfurtransferase activity | SULT2ST1,TRMU |
protein binding | SORBS2,HIP1R,PLLP,FZD8,RSU1,TPX2,RHEBL1,ARHGAP9,CSPP1,CCDC146 |
Interacting Protein
MOCS3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MOCS3 here. Most of them are supplied by our site. Hope this information will be useful for your research of MOCS3.
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References
- Mendel, RR; Leimkuhler, S; et al. The biosynthesis of the molybdenum cofactors. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 20:337-347(2015).
- Matsumoto, T; Yano, H; et al. Syntheses and Structures of Molybdenum-Oxo Complexes Prepared by the Reactions of [Mo-2(II)(OAc)(4)] with tert-Butyl- or Bromo-Substituted Catechols. BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN 88:74-83(2015).