LTA4H
-
Official Full Name
leukotriene A4 hydrolase -
Overview
Hydrolyzes an epoxide moiety of leukotriene A4 (LTA-4) to form leukotriene B4 (LTB-4). The enzyme also has some peptidase activity. -
Synonyms
LTA4H;leukotriene A4 hydrolase;leukotriene A-4 hydrolase;LTA-4 hydrolase;FLJ17564
Recombinant Proteins
- Mouse
- Human
- Zebrafish
- Chicken
- Insect Cells
- Mammalian Cell
- HEK293
- E.coli
- Insect Cell
- Mammalian cells
- HEK293T
- Wheat Germ
- In Vitro Cell Free System
- His
- His&T7
- Non
- Flag
- Myc&DDK
- His&Fc&Avi
- GST
Involved Pathway
LTA4H involved in several pathways and played different roles in them. We selected most pathways LTA4H participated on our site, such as Arachidonic acid metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with LTA4H were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Arachidonic acid metabolism | CYP2B19,GPX1A,CYP2C39,PTGDSB,HPGDS,GGT1A,PTGES3,AKR1C6,MAPKAPK2B,PTGDSA |
| Metabolic pathways | QDPRA,GNPDA2,CYP27A1,GFPT1,PC,IMPDH1A,CMPK,TK2,NDST2,KLF15 |
Protein Function
LTA4H has several biochemical functions, for example, aminopeptidase activity,epoxide hydrolase activity,leukotriene-A4 hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LTA4H itself. We selected most functions LTA4H had, and list some proteins which have the same functions with LTA4H. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| peptide binding | FURIN,OXTR,IDE,ERCC3,AVPR2,CRHBP,GNRHR2,NPFFR1L1,GNRHR1,NLN |
| epoxide hydrolase activity | EPHX1,RNPEP,EPHX4,EPHX3,Npepo,EPHX2 |
| aminopeptidase activity | NPEPPS,NPEPL1,XPNPEP3,DPP9,METAP2,ERAP2,CTSL2,BLMH,Npepo,METAP1D |
| poly(A) RNA binding | MRPL28,MEPCE,DEK,NUPL2,HNRNPUL1,LRPPRC,YTHDC2,RBM26,MRPL4,RPP25L |
| peptidase activity | MPND,USP9,FAP,GZMC,NPEPPS,ZMPSTE24,BACE1,PRSS44,CTSSB.2,GM5077 |
| zinc ion binding | NR4A2A,BTR09,KNG1,ADAM17,RNF32,PPARDB,PRKCBA,ANKIB1A,ADAM28,PRKCG |
| metalloaminopeptidase activity | LNPEP,RNPEPL1,ANPEPA,ANPEPB,XPNPEP1,ENPEP,TRHDE,METAP2A,METAP2B,ANPEP |
| protein binding | GAGE5,C1QTNF8,POLR1C,NDUFB11,ZC4H2,CTNNB1,SELP,TMEM147,NELL2,TOMM22 |
Interacting Protein
LTA4H has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LTA4H here. Most of them are supplied by our site. Hope this information will be useful for your research of LTA4H.
TINF2;GH1;MCC;HLA-B;HLA-C;IKBKE;DDA1;UBA5;ARPC3;TMEM62;q8d0m8_yerpe
Resources
Research Area
Eicosanoids and RegulatorsInflammatory Mediators
Leukotriene Metabolism
Metalloproteases and Regulators
Related Services
Related Products
References
