LILRA3
-
Official Full Name
leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 -
Overview
Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and;at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function;(see, e.g., LILRB1, MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor;tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may;initiate stimulatory cascades (see LILRA1, MIM 604810). One member of subfamily A (LILRA3) lacks a transmembrane;region and is presumed to be a soluble receptor (Borges et al., 1997 (PubMed 9548455)). -
Synonyms
LILRA3;leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3;leukocyte immunoglobulin-like receptor subfamily A member 3;CD85e;HM31;HM43;ILT6;LIR 4;LIR4;CD 85E;CD85 antigen-like family member E;CD85e antigen;e3;HM 31;HM 43;ILT 6;ILT-6;Immunoglobulin like transcript 6;Immunoglobulin-like transcript 6;Leucocyte immunoglobulin like receptor;Leukocyte immunoglobulin like receptor 4;Leukocyte immunoglobulin like receptor A3;Leukocyte immunoglobulin like receptor subfamily A (without TM domain) member 3;Leukocyte immunoglobulin like receptor subfamily A member 3;Leukocyte immunoglobulin-like receptor 4;LILRA 3;LIR-4;LIRA3_HUMAN;Monocyte inhibitory receptor HM43/HM31;OTTHUMP00000067955;OTTHUMP00000067956;OTTHUMP00000067957;leucocyte immunoglobulin-like receptor;monocyte inhibitory recept
Recombinant Proteins
- Human
- Rhesus macaque
- HEK293
- Mammalian Cell
- Human Cell
- E.coli
- Mammalian cells
- HEK293T
- His&Avi
- HIS
- Non
- Fc
- hIgG4
- His
- His&Fc
- His&T7
- C-His&Fc
- His&Fc&Avi
- Myc&DDK
Involved Pathway
LILRA3 involved in several pathways and played different roles in them. We selected most pathways LILRA3 participated on our site, such as Adaptive Immune System,Immune System,Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with LILRA3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Immune System | PANX1,UFL1,CD300LF,PELI2,IFITM3,CFHL3,SUGT1,KIF4A,KIF4,CLEC5A |
| Osteoclast differentiation | MAP3K14,TNFRSF11A,PIK3R3,FCGR1A,MITF,STAT1,PIK3CB,SOCS1,FYN,LCK |
| Adaptive Immune System | LAIR1,UFL1,PTBP3,DCTN3,CD300LB,AGO2,DCTN2,AP2S1,SIGLEC6,CD300A |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | RAET1E,GM11711,CD300A,CD300LH,LAIR1,ICAM4,SIGLEC12,LILRB3,SLAMF6,LILRB5 |
Protein Function
LILRA3 has several biochemical functions, for example, antigen binding,receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LILRA3 itself. We selected most functions LILRA3 had, and list some proteins which have the same functions with LILRA3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| receptor activity | PROCR,ATRN,IL18R1,THRAP3,CD226,NR2C1,RPA1,TREM1,LRRN2,CSF2RA |
| antigen binding | IGKV1-5,IGHM,TSPAN4,HNRNPM,LILRA2,Ighg,TOPORS,LILRB4,LCK,MHC1UKA |
Interacting Protein
LILRA3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LILRA3 here. Most of them are supplied by our site. Hope this information will be useful for your research of LILRA3.
EWSR1
Resources
Research Area
ITIM/ITAM Immunoreceptors and Related MoleculesCo-stimulatory ILT/CD85 Family Proteins
T Cell Antigen Recognition
Co-stimulatory Molecules
Macrophage Markers
Monocyte Markers
Other Proteins Involved in Regulating B Cell Activation
Dendritic Cell Activation
Related Services
Related Products
References
