KRT14
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Official Full Name
KRT14 keratin 14 -
Synonyms
KRT14;keratin 14;EBS3, EBS4, keratin 14 (epidermolysis bullosa simplex, Dowling Meara, Koebner);keratin, type I cytoskeletal 14;epidermolysis bullosa simplex;Dowling Meara;Koebner;CK-14;keratin-14;cytokeratin 14;cytokeratin-14;keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner);K14;NFJ;CK14;EBS3;EBS4
Recombinant Proteins
- Human
- Chicken
- Mouse
- Rat
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- Yeast
- In Vitro Cell Free System
- His
- GST
- Non
- His&T7
- His&Fc&Avi
- His&SUMO
Involved Pathway
KRT14 involved in several pathways and played different roles in them. We selected most pathways KRT14 participated on our site, such as Corticotropin-releasing hormone,Glucocorticoid receptor regulatory network, which may be useful for your reference. Also, other proteins which involved in the same pathway with KRT14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glucocorticoid receptor regulatory network | EGR1,SMARCD1,SMARCC2,KRT5,POU2F1,NR1I3,SMARCA4,KRT17,CSN2,BGLAP |
| Corticotropin-releasing hormone | ADRBK2,CYP11A1,JUND,PARP1,CYP11B1,TCF4,TFAP2A,CASP12,CRHBP,TRIM28 |
Protein Function
KRT14 has several biochemical functions, for example, keratin filament binding,protein binding,structural constituent of cytoskeleton. Some of the functions are cooperated with other proteins, some of the functions could acted by KRT14 itself. We selected most functions KRT14 had, and list some proteins which have the same functions with KRT14. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| structural constituent of cytoskeleton | TUBE1,INA,ARPC2,YEATS4,KRT15,ACTR3,TUBA2,BICD1,TUBGCP2,TUBA3C |
| keratin filament binding | SIRT1,VIM |
| protein binding | NAV2,ACE,NOP58,FBXO46,PYY,AREG,THOC1,GSTO2,KIF2C,RBP7 |
Interacting Protein
KRT14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KRT14 here. Most of them are supplied by our site. Hope this information will be useful for your research of KRT14.
PKP1;PPP2R2B;KRT5;PKP2;HSPA5;APC;TRADD;midostaurin;E2F3;GABARAP;EGFR;IGHG1;IGHA1;ALB;EIF4A3;GABARAPL2
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References
- Torchia, EC; Zhang, L; et al. Aurora Kinase-A Deficiency during Skin Development Impairs Cell Division and Stratification. JOURNAL OF INVESTIGATIVE DERMATOLOGY 133:78-86(2013).
- Guzvic, M; Braun, B; et al. Combined Genome and Transcriptome Analysis of Single Disseminated Cancer Cells from Bone Marrow of Prostate Cancer Patients Reveals Unexpected Transcriptomes. CANCER RESEARCH 74:7383-7394(2014).
