KDM5B

  • Official Full Name

    lysine (K)-specific demethylase 5B

  • Overview

    Lysine-specific demethylase 5B also known as histone demethylase JARID1B is a demethylase enzyme that in humans is encoded by the KDM5B gene.

  • Synonyms

    CT31;PLU1;PUT1;PLU-1;JARID1B;FLJ10538;FLJ12459;FLJ12491;FLJ16281;FLJ23670;RBBP2H1A;lysine-specific demethylase 5B;RBP2-H1;OTTHUMP00000038815;OTTHUMP00000038816;OTTHUMP00000197658;cancer/testis antigen 31;histone demethylase JARID1B;putative DNA/chromatin binding motif;jumonji, AT rich interactive domain 1B;jumonji/ARID domain-containing protein 1B;retinoblastoma-binding protein 2 homolog 1;retinoblastoma-binding protein 2, homolog 1A;KDM5B;lysine (K)-specific demethylase 5B

Recombinant Proteins

  • Human
  • Mouse
  • Chicken
  • E.coli
  • Sf9 Insect Cell
  • Mammalian Cell
  • HEK293
  • His
  • Flag
  • GST
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
KDM5B-3798H Recombinant Human KDM5B protein, His-tagged E.coli Human His 190-309 aa
KDM5B-44H Active Recombinant Human KDM5B, FLAG-tagged Sf9 Insect Cell Human Flag
Kdm5b-261M Recombinant Mouse Kdm5b, GST-tagged Sf9 Insect Cell Mouse GST 1-753 a.a.
KDM5B-2709C Recombinant Chicken KDM5B Mammalian Cell Chicken His
KDM5B-752H Recombinant Human KDM5B Mammalian Cell Human His
KDM5B-8595M Recombinant Mouse KDM5B Protein Mammalian Cell Mouse His
KDM5B-4992HCL Recombinant Human KDM5B 293 Cell Lysate HEK293 Human Non
KDM5B-301312H Recombinant Human KDM5B protein, GST-tagged E.coli Human GST Ser190-Leu309
KDM5B-3200H Recombinant Human KDM5B Protein, His (Fc)-Avi-tagged HEK293 Human His&Fc&Avi
KDM5B-3200H-B Recombinant Human KDM5B Protein Pre-coupled Magnetic Beads HEK293 Human
KDM5B-4783M Recombinant Mouse KDM5B Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
KDM5B-4783M-B Recombinant Mouse KDM5B Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    KDM5B involved in several pathways and played different roles in them. We selected most pathways KDM5B participated on our site, such as Chromatin modifying enzymes,Chromatin organization,HDMs demethylate histones, which may be useful for your reference. Also, other proteins which involved in the same pathway with KDM5B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Chromatin organization ATXN7,SMARCC1,ING3,PAX3A,PADI3,KAT7A,ZZZ3,PHF17,ARID5B,KDM3A
    HDMs demethylate histones KDM3B,KDM4A,KDM1A,KDM5BA,KDM5A,ARID5B,KDM5C,PHF8,KDM6B,JMJD6
    Chromatin modifying enzymes MBD3A,KDM1A,KDM4C,MSL3,SETD3,ARID1A,KANSL3,MBD3B,BRMS1,KDM4A

    Protein Function

    KDM5B has several biochemical functions, for example, DNA binding,histone demethylase activity (H3-K4 specific),histone demethylase activity (H3-dimethyl-K4 specific). Some of the functions are cooperated with other proteins, some of the functions could acted by KDM5B itself. We selected most functions KDM5B had, and list some proteins which have the same functions with KDM5B. You can find most of the proteins on our site.

    Function Related Protein
    oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors KDM5BA,KDM5C,TYW5,PHF8,KDM5A,ALKBH8,EGLN2,KDM5D,P4HTM,ALKBH4
    transcription corepressor activity HOXC6,ATF5,NEUROD2,TLE4,SSX4,SUFU,C1D,ZHX2,NSD1,IRF2BP2
    histone demethylase activity (H3-dimethyl-K4 specific) KDM1A,KDM5BB,KDM1B
    histone demethylase activity (H3-trimethyl-K4 specific) KDM5BB
    zinc ion binding MMP12,TRIP6,ZDHHC14,ZFP598,RNF34A,RNF152,MAN2B2,LIMS3L,GFI1AA,ZYX
    histone demethylase activity (H3-K4 specific) KDM1A,KDM5D,KDM5C,C14orf169
    transcription factor activity, sequence-specific DNA binding SCAND1,PLAGL2,UBN2A,DMRT1,SLAMF7,WT1,RBPJB,ZNF821,NFATC2,CSDA
    DNA binding POU6F2,SALL1,HIST4H4,CARHSP1,SUPT3H,FOXG1D,CEBPA,ZFP184,ARHGAP35,NKX2.4A
    protein binding DOK2,ZNF572,MOV10,ARNTL1B,MYOZ1,KDR,ARF6,FUBP3,ZFPM1,NDFIP2

    Interacting Protein

    KDM5B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KDM5B here. Most of them are supplied by our site. Hope this information will be useful for your research of KDM5B.

    CTCF;PPP1CA;PRPF4;brca1_human_gene;CDC14A;TGFB2;ESRP1;CAV1;PALD1;ctgf_human_gene;CHST3;PTGIS

    Resources

    Research Area

    Histone Demethylases

    References

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