ING3
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Official Full Name
inhibitor of growth family, member 3 -
Synonyms
ING3;inhibitor of growth family, member 3;inhibitor of growth protein 3;Eaf4;FLJ20089;MEAF4;p47ING3;ING2
Recombinant Proteins
- Human
- Zebrafish
- Chicken
- Rat
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- GST
- His
- Non
- Avi&Fc&His
- DDK&Myc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ING3-112H | Recombinant Human ING3, GST-tagged | E.coli | Human | GST | N-term-92aa | |
| ING3-3884H | Recombinant Human ING3 protein, His-tagged | E.coli | Human | His | 1-92 aa | |
| ING3-11176Z | Recombinant Zebrafish ING3 | Mammalian Cells | Zebrafish | His |
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| ING3-2434C | Recombinant Chicken ING3 | Mammalian Cells | Chicken | His |
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| ING3-3063R | Recombinant Rat ING3 Protein | Mammalian Cells | Rat | His |
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| ING3-8209M | Recombinant Mouse ING3 Protein | Mammalian Cells | Mouse | His |
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| ING3-5207HCL | Recombinant Human ING3 293 Cell Lysate | HEK293 | Human | Non |
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| ING3-2719R | Recombinant Rat ING3 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | Avi&Fc&His |
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| ING3-2719R-B | Recombinant Rat ING3 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| ING3-301316H | Recombinant Human ING3 protein, GST-tagged | E.coli | Human | GST | Met1-Phe92 |
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| Ing3-3537M | Recombinant Mouse Ing3 Protein, Myc/DDK-tagged | HEK293 | Mouse | DDK&Myc |
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| ING3-4544M | Recombinant Mouse ING3 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| ING3-4544M-B | Recombinant Mouse ING3 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| ING3-5129H | Recombinant Human ING3 Protein, GST-tagged | Wheat Germ | Human | GST |
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| ING3-5876HF | Recombinant Full Length Human ING3 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 92 amino acids |
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Involved Pathway
ING3 involved in several pathways and played different roles in them. We selected most pathways ING3 participated on our site, such as Chromatin modifying enzymes,Chromatin organization,HATs acetylate histones, which may be useful for your reference. Also, other proteins which involved in the same pathway with ING3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| HATs acetylate histones | CAPNS2,ATXN7L3,BRD8,SAP130,TADA2A,YEATS4,KAT8,ANO9A,BRPF3,VPS72 |
| Chromatin modifying enzymes | MBD3B,PADI6,BRPF1,CHD4,SUZ12A,MTA3,MTA1,ARID4A,RBBP5,PHF17 |
| Chromatin organization | TADA3,DR1,ING5,MBD3A,C3orf75,C20orf20,SMARCD3B,PRMT5,PHF17,PADI2 |
Protein Function
ING3 has several biochemical functions, for example, contributes_to histone acetyltransferase activity,methylated histone binding,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ING3 itself. We selected most functions ING3 had, and list some proteins which have the same functions with ING3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| contributes_to histone acetyltransferase activity | TADA2B,TEX30,SUPT7L,TAF5L,TAF6L,ELP4,TADA1,TAF12,TAF9,TADA3 |
| methylated histone binding | TP53BP1,FAM156A,WDR92,KDM4A,UHRF1,L3MBTL1,RAG2,DPPA3,ING4,SUZ12 |
| zinc ion binding | RNF213,ADAM1B,ZMYM5,ZNF638,USP3,MORC1,MMP15,S100A13,ZBTB32,PDLIM5 |
Interacting Protein
ING3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ING3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ING3.
MRGBP;VPS72;RUVBL2;TRRAP;DNAJB5;KAT7;YEATS4;ACTL6A;SNRPA1;HSPA5;PLD1;EPC2;NKAP;JADE3
Resources
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References
- Mishra, R; Kumar, D; et al. The potential of class 3 semaphorins as both targets and therapeutics in cancer. EXPERT OPINION ON THERAPEUTIC TARGETS 19:427-442(2015).
- Bharadwaj, U; Eckols, TK; et al. Drug-repositioning screening identified piperlongumine as a direct STAT3 inhibitor with potent activity against breast cancer. ONCOGENE 34:1341-1353(2015).
