IL9R
-
Official Full Name
interleukin 9 receptor -
Overview
The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene. -
Synonyms
IL9R;interleukin 9 receptor;interleukin-9 receptor;CD129;IL-9R;IL-9 receptor
Recombinant Proteins
- Rat
- Human
- Mouse
- Mammalian cells
- HEK293
- E.coli
- Human Cell
- Wheat Germ
- In Vitro Cell Free System
- His
- His&T7
- Non
- His&Fc&Avi
- GST
- Fc
Involved Pathway
IL9R involved in several pathways and played different roles in them. We selected most pathways IL9R participated on our site, such as Cytokine-cytokine receptor interaction,Hematopoietic cell lineage,IL-9 Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL9R were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Hematopoietic cell lineage | CD38,IL5,IL1B,CD1B,ITGA3,Itga10&Itgb1,TNF,CD36,HLA-DRB4,CD34 |
| Cytokine-cytokine receptor interaction | IL7R,TNFRSF11A,FAS,TNFSF9,IFNA12,IL21R.1,CXCL1,TNF,CCR7,ACKR3B |
| Jak-STAT signaling pathway | Ifnlr1,IL2RG,PTPN11,PIK3CG,IL5RA,PTPN2,MCL1A,SOCS5B,PIAS4B,GFAP |
Protein Function
IL9R has several biochemical functions, for example, interleukin-9 receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IL9R itself. We selected most functions IL9R had, and list some proteins which have the same functions with IL9R. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
IL9R has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL9R here. Most of them are supplied by our site. Hope this information will be useful for your research of IL9R.
YWHAZ;CRADD
Resources
Research Area
Negative Regulators of the Jak/STAT PathwayReceptors in the Jak/STAT Pathway
Common gamma Chain Family Receptors
Related Services
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References
