IL1F8
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Official Full Name
interleukin 36, beta -
Overview
The protein encoded by this gene is a member of the interleukin 1 cytokine family. Protein structure modeling indicated that this cytokine may contain a 12-stranded beta-trefoil structure that is conserved between IL1A (IL-A alpha) and IL1B (IL-1 beta). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. -
Synonyms
FIL1;FIL1H;IL1F8;IL1H2;IL-1F8;IL-1H2;IL1-ETA;FIL1-(ETA);FILI-(ETA)
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Il1f8-745M | Recombinant Mouse Il1f8 protein | E.coli | Mouse | Non | Met1-Lys183 |
|
Involved Pathway
IL1F8 involved in several pathways and played different roles in them. We selected most pathways IL1F8 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with IL1F8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
IL1F8 has several biochemical functions, for example, cytokine activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IL1F8 itself. We selected most functions IL1F8 had, and list some proteins which have the same functions with IL1F8. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cytokine activity | HMGB1,VSTM1,VEGFA,TNF,Ifnl2,NDP,CCL6,Ccl9,Ccl12,OSTN |
Interacting Protein
IL1F8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL1F8 here. Most of them are supplied by our site. Hope this information will be useful for your research of IL1F8.
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References
- Mehrotra, S; Pecaut, MJ; et al. Minocycline Modulates Cytokine and Gene Expression Profiles in the Brain After Whole-body Exposure to Radiation. IN VIVO 28:21-32(2014).
- Gao, F; Zhao, ZL; et al. miR-9 modulates the expression of interferon-regulated genes and MHC class I molecules in human nasopharyngeal carcinoma cells. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 431:610-616(2013).
