HTR1E

  • Official Full Name

    5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
  • Overview

    5-hydroxytryptamine (serotonin) 1E receptor (5-HT1E) is a highly expressed human G-protein coupled receptor that belongs to the 5-HT1 receptor family (Gi-coupled serotonin receptor). The human gene is denoted as HTR1E.
  • Synonyms

    HTR1E;5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled;5 hydroxytryptamine (serotonin) receptor 1E;5-hydroxytryptamine receptor 1E;5 HT1E;S31;5-HT-1E;serotonin receptor 1E;5-HT1E

Recombinant Proteins

  • Human
  • Sus scrofa (Pig)
  • Pan troglodytes
  • HEK293
  • Wheat Germ
  • In Vitro Cell Free System
  • E.coli
  • Non
  • His&Flag
  • GST
  • His
Cat.# Product name Source (Host) Species Tag Protein Length Price
HTR1E-5336HCL Recombinant Human HTR1E 293 Cell Lysate HEK293 Human Non
HTR1E-1089HFL Recombinant Human HTR1E protein, His&Flag-tagged HEK293 Human His&Flag 1-365 aa
HTR1E-5247H Recombinant Human HTR1E Protein, GST-tagged Wheat Germ Human GST
HTR1E-5248H Recombinant Human HTR1E Protein Wheat Germ Human Non
HTR1E-5678HF Recombinant Full Length Human HTR1E Protein In Vitro Cell Free System Human Full L. 404 amino acids
HTR1E-5680HF Recombinant Full Length Human HTR1E Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 365 amino acids
RFL10440SF Recombinant Full Length Pig 5-Hydroxytryptamine Receptor 1E(Htr1E) Protein, His-Tagged E.coli Sus scrofa (Pig) His Full L. Full Length (1-149)
RFL17577HF Recombinant Full Length Human 5-Hydroxytryptamine Receptor 1E(Htr1E) Protein, His-Tagged E.coli Human His Full L. Full Length (1-365)
RFL27491PF Recombinant Full Length Pan Troglodytes 5-Hydroxytryptamine Receptor 1E(Htr1E) Protein, His-Tagged E.coli Pan troglodytes His Full L. Full Length (1-363)

    Involved Pathway

    HTR1E involved in several pathways and played different roles in them. We selected most pathways HTR1E participated on our site, such as cAMP signaling pathway,Neuroactive ligand-receptor interaction,Serotonergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with HTR1E were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Serotonergic synapse ITPR1,PRKCA,CYP2C55,HTR1B,ALOX15,HTR1F,ARAF,PLA2G4A,ALOX12B,CYP2C38
    cAMP signaling pathway GHRL,PLCE1,SUCNR1,MAP2K1,VIPR2,VAV1,ATP2B1,PRKACB,FOS,PLD1
    Neuroactive ligand-receptor interaction GRM6B,MC1R,RXFP4,CHRNB2,GLRA2,CHRNB3,SSTR1,GLRB,GABRR3A,ADRB2A

    Protein Function

    HTR1E has several biochemical functions, for example, G-protein coupled receptor activity,protein binding,serotonin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HTR1E itself. We selected most functions HTR1E had, and list some proteins which have the same functions with HTR1E. You can find most of the proteins on our site.

    Function Related Protein
    protein binding CCT7,SESN2,PLK1S1,NR2E3,TGFB1,BCL2L14,FAM118B,SAFB2,MTAP1B,GNG12
    serotonin binding HTR2A,HTR1F,HTR2B,HTR1B,MAOA,HTR2C,HTR3A
    serotonin receptor activity HTR1AA,HTR3C,HTR3A,HTR3B,HTR1F,HTR1A,HTR1B,HTR5A,HTR2C,HTR2B
    G-protein coupled receptor activity GPR171,GRM6A,S1PR1,VMN1R46,ADRA2DB,MLNR,TAS2R120,OR10A4,ADRB2A,FFAR2

    Interacting Protein

    HTR1E has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HTR1E here. Most of them are supplied by our site. Hope this information will be useful for your research of HTR1E.

    MEOX2;PSMC3;PSMC4

    Resources

    Research Area

    5-HT Receptors

    References

    • Jin, Y; Wang, LM; et al. Differential expression of 5-HT-related genes in symptomatic pulmonary embolism patients. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE 8:512-518(2015).
    • Shoval, G; Bar-Shira, O; et al. Transitions in the transcriptome of the serotonergic and dopaminergic systems in the human brain during adolescence. EUROPEAN NEUROPSYCHOPHARMACOLOGY 24:1123-1132(2014).

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