HSF4
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Official Full Name
heat shock transcription factor 4 -
Overview
Heat-shock transcription factors (HSFs) activate heat-shock response genes under conditions of heat or other stresses.HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described. -
Synonyms
HSF4;heat shock transcription factor 4;cataract, Marner , CTM;heat shock factor protein 4;HSF 4;hHSF4;HSTF 4;CTM
Recombinant Proteins
- Zebrafish
- Human
- Chicken
- Mouse
- Rat
- Mammalian Cells
- Wheat Germ
- E.coli
- His
- Non
- GST
- His&GST
- His&T7
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HSF4-2111Z | Recombinant Zebrafish HSF4 | Mammalian Cells | Zebrafish | His |
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| HSF4-29388TH | Recombinant Human HSF4 | Wheat Germ | Human | Non | 100 amino acids |
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| HSF4-4064C | Recombinant Chicken HSF4 | Mammalian Cells | Chicken | His |
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| HSF4-5091H | Recombinant Human HSF4 Protein, GST-tagged | Wheat Germ | Human | GST |
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| HSF4-5662H | Recombinant Human HSF4 protein, His & GST-tagged | E.coli | Human | His&GST | Val171~Arg284 |
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| Hsf4-5663M | Recombinant Mouse Hsf4 protein, His & T7-tagged | E.coli | Mouse | His&T7 | Glu159~Asp411 |
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| Hsf4-5664R | Recombinant Rat Hsf4 protein, His & T7-tagged | E.coli | Rat | His&T7 | Leu91~Met407 |
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| HSF4-716H | Recombinant Human HSF4 Protein, His-tagged | E.coli | Human | His |
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| HSF4-821HCL | Recombinant Human HSF4 cell lysate | Human | Non |
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| HSF4-2675H | Recombinant Human HSF4 Protein (Val171-Arg284), N-GST tagged | E.coli | Human | GST | Val171-Arg284 |
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Involved Pathway
HSF4 involved in several pathways and played different roles in them. We selected most pathways HSF4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HSF4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
HSF4 has several biochemical functions, for example, protein phosphatase binding,sequence-specific DNA binding,transcription corepressor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HSF4 itself. We selected most functions HSF4 had, and list some proteins which have the same functions with HSF4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| sequence-specific DNA binding | ZNF205,TCF3A,FEV,ZSCAN23,MNX1,FOXO3A,HOXD9A,HOXB6A,RAB11FIP4A,BSX |
| protein phosphatase binding | ROS1,ITPR1,IRS2,JUPA,RPA2,ANAPC5,SHOC2,PPP6R1,TRP53,PPP1R3C |
| transcription corepressor activity | SKOR2,NPAT,UBP1,TRIM28,SSX3,C1QBP,PPP1R13L,ARHGAP35,PROX1,TLE4 |
| transcription factor activity, sequence-specific DNA binding | ZFP30,SUPT6H,ZFP628,ZNF35,ZBTB25,E2F7,ZNF565,PBX3B,FOSL1A,ZFP13 |
Interacting Protein
HSF4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HSF4 here. Most of them are supplied by our site. Hope this information will be useful for your research of HSF4.
NUDT21;CDK2AP2;ZBED8;BCL6;HSF1;HSF2;TARBP1;FKBP5;RABEP1;SESTD1;MYO15A;SUGT1;TIMM13
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