HECTD3
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Official Full Name
HECT domain containing 3 -
Synonyms
HECTD3;HECT domain containing 3;E3 ubiquitin-protein ligase HECTD3;FLJ21156;HECT;HECT domain containing protein 3;Probable E3 ubiquitin protein ligase HECTD3;HECT domain-containing protein 3;probable E3 ubiquitin-protein ligase HECTD3;RP11-69J16.1
Recombinant Proteins
- Human
- Rhesus macaque
- Zebrafish
- Mouse
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- Avi&Fc&His
- DDK&Myc
Involved Pathway
HECTD3 involved in several pathways and played different roles in them. We selected most pathways HECTD3 participated on our site, such as Adaptive Immune System,Antigen processing: Ubiquitination &,Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with HECTD3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Immune System | DEFA3,IRF9,KIFAP3,GBP6,MB21D1,DEFB4B,OSBPL1A,NLRP4B,CR1,HBL3 |
| Class I MHC mediated antigen processing & | FBXO17,TRIM11,ASB17,FBXO44,UFL1,PJA1,HUWE1,CD207,TRAF7,TRIM69 |
| Proteasome degradation | ASB13,SPSB1,TRIM63,LRRC41,VPRBP,RBCK1,RNF123,NPEPPS,TRIM69,TRAF7 |
| presentation | CD207,ASB10,PJA2,LRR1,RBCK1,RNF144B,CYBB,RNF25,UBR2,RNF182 |
| Adaptive Immune System | CTSL2,UBE2U,ASB6,CLEC2B,PTBP3,AGO3,FRS2,KLRF1,LILRA3,KIFAP3 |
| Antigen processing: Ubiquitination & | RNF34,FBXO3,UBE2U,ATG7,KLHL21,ASB13,ARIH2,TRIM41,ASB6,CMTM2A |
Protein Function
HECTD3 has several biochemical functions, for example, ligase activity,protein binding,syntaxin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HECTD3 itself. We selected most functions HECTD3 had, and list some proteins which have the same functions with HECTD3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ubiquitin-protein transferase activity | TRIM37,TRAF3,TNFAIP3,HECW1B,TRIM62,MGRN1,BRAP,FBXO9,ANKIB1,CBLB |
| ligase activity | TRIM13,G2E3,BTRC,RNF213,RLIM,HERC2,PARK2,TRIM31,ITCHA,RAD18 |
| syntaxin binding | TXLNBB,STXBP5L,CPLX3,VAMP2,STX8,VAMP7,STXBP1,NAPB,RPH3AL,ABCA1 |
| ubiquitin protein ligase activity | UBE2Z,RNF181,TRIM72,MED27,ZNRF2,UBE2B,CDC34,UBE2G2,CCNB1IP1,HERC3 |
| protein binding | MYBPC2,POLR2J,FOXC1,NFKBIL2,STK25,SCN5A,USP14,RPA3,PTTG1IP,RPAP1 |
Interacting Protein
HECTD3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HECTD3 here. Most of them are supplied by our site. Hope this information will be useful for your research of HECTD3.
HSP90AB1;SMAD2;ZDHHC17;MAVS
Resources
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References
- Liu, ZQ; Oughtred, R; et al. Characterization of E3(Histone), a novel testis ubiquitin protein ligase which ubiquitinates histones. MOLECULAR AND CELLULAR BIOLOGY 25:2819-2831(2005).
