GZMK
-
Official Full Name
granzyme K (granzyme 3 -
Overview
This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface nonself antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes. [provided by RefSeq, Jul 2008] -
Synonyms
GZMK;granzyme K (granzyme 3;tryptase II);TRYP2;granzyme K;NK-Tryp-2;granzyme 3;granzyme-3;tryptase II;fragmentin-3;NK-tryptase-2;granzyme K (serine protease, granzyme 3;tryptase II)
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Mouse
- Insect Cells
- Mammalian Cells
- E.coli
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- Insect cells
- His
- Non
- GST
- His&Myc
- His&Fc&Avi
Involved Pathway
GZMK involved in several pathways and played different roles in them. We selected most pathways GZMK participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GZMK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
GZMK has several biochemical functions, for example, serine-type endopeptidase activity,serine-type peptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GZMK itself. We selected most functions GZMK had, and list some proteins which have the same functions with GZMK. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| serine-type endopeptidase activity | GM5077,TPSAB1,TMPRSS11D,LPA,CFI,C1R,FAM108A1,MBTPS1,KLK11,FURINA |
| serine-type peptidase activity | DPP4,MCPT2,HPN,TPSB2,KLK15,PRSS40,KLK1B3,Acr,IRBP,SEC11C |
Interacting Protein
GZMK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GZMK here. Most of them are supplied by our site. Hope this information will be useful for your research of GZMK.
LIG4;PNKP
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