GPR15
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Official Full Name
G protein-coupled receptor 15 -
Overview
G-protein coupled receptor 15 is a protein that in humans is encoded by the GPR15 gene. Probable chemokine receptor. Alternative coreceptor with CD4 for HIV-1 infection. -
Synonyms
GPR15;G protein-coupled receptor 15;G-protein coupled receptor 15;BOB;brother of Bonzo;MGC126828;MGC126830
Recombinant Proteins
- Rhesus macaque
- Human
- Cynomolgus
- Mouse
- Zebrafish
- Macaca fascicularis
- Macaca nemestrina (Pig-tailed macaque)
- Pan troglodytes
- Macaca mulatta
- Mus musculus
- Mammalian Cell
- E.coli
- HEK293
- HEK293T
- Wheat Germ
- In Vitro Cell Free System
- In vitro E. coli expression system
- E.coli expression system
- His
- Myc&DDK
- Non
- GST
- His&Fc&Avi
Involved Pathway
GPR15 involved in several pathways and played different roles in them. We selected most pathways GPR15 participated on our site, such as Non-odorant GPCRs, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPR15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Non-odorant GPCRs | OPN3,GPR132,BAI2,O3far1,EMR4,RRH,CELSR3,CELSR1 |
Protein Function
GPR15 has several biochemical functions, for example, G-protein coupled receptor activity,signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GPR15 itself. We selected most functions GPR15 had, and list some proteins which have the same functions with GPR15. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| G-protein coupled receptor activity | GPR88,AVPR2L,TAAR14E,TAS2R136,TAAR11,OR2B3,LPAR2,OR6B2,APLNRB,MRGPRX1 |
| signal transducer activity | ACKR3B,GPR126,TAS2R201.1,TAS2R116,TAAR14A,PLCD3,TAS2R140,CXXC5,GNB5,GNA12 |
Interacting Protein
GPR15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPR15 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPR15.
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References
- Xu, Y; Weatherall, C; et al. Simian Immunodeficiency Virus Infects Follicular Helper CD4 T Cells in Lymphoid Tissues during Pathogenic Infection of Pigtail Macaques. JOURNAL OF VIROLOGY 87:3760-3773(2013).
- Jiang, CL; Parrish, NF; et al. Primary Infection by a Human Immunodeficiency Virus with Atypical Coreceptor Tropism. JOURNAL OF VIROLOGY 85:10669-10681(2011).
