ESR2
-
Official Full Name
ESR2 estrogen receptor 2 (ER beta) -
Synonyms
ESR2;estrogen receptor 2 (ER beta);estrogen receptor beta;Erb;NR3A2;estrogen receptor beta 4;estrogen nuclear receptor beta variant a;estrogen nuclear receptor beta variant b;nuclear receptor subfamily 3 group A member 2;ESRB;ESTRB;ER-BETA;ESR-BETA
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Mouse
- Chicken
- E.coli
- Sf9 Cells
- Mammalian Cells
- Wheat Germ
- HEK293
- Yeast
- In Vitro Cell Free System
- GST
- His
- Non
- Flag
- Avi&Fc&His
- His&SUMO
Involved Pathway
ESR2 involved in several pathways and played different roles in them. We selected most pathways ESR2 participated on our site, such as Estrogen signaling pathway,Prolactin signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ESR2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Estrogen signaling pathway | PIK3R1,GNAS,MAP2K1,GABBR1,HSP90AB1,KRAS,SRC,GNAQ,SHC3,KCNJ5 |
| Prolactin signaling pathway | PIK3CG,TH,SOCS3,STAT5B,MAPK12,MAPK13,MAPK3,PPIB,CCND2,INS1 |
Protein Function
ESR2 has several biochemical functions, for example, DNA binding,RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding,core promoter sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ESR2 itself. We selected most functions ESR2 had, and list some proteins which have the same functions with ESR2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| steroid hormone receptor activity | RARGB,NR2F1A,PGRMC2,HNF4A,RARA,NR5A2,NR5A1A,RARAA,RXRGA,NR2F6 |
| steroid binding | ESRRGA,ESR1,CYP21A2,ESRRGB,PAQR5A,AKR1D1,ESR2A,NR3C1,ESRRG,HSD3B4 |
| DNA binding | ZBTB18,HOXD12,H2BFWT,NKX2-5,CSDC2A,TSHZ3,HMGN5,POU4F2,PNN,ZNF155 |
| estrogen response element binding | TRIM24,TOX3,ESR1 |
| transcription factor activity, sequence-specific DNA binding | NR1H5,DLX2,RXRBA,E2F2,NR2C2,TBP,PPARDB,HOXB6A,HNF1BB,NR5A2 |
| zinc ion binding | ZNRF1,WBP2NL,SEC23B,ING1,ADH6,RNF13,NR1D2A,RNF113B,LHX8,RABGGTA |
| estrogen receptor activity | ESR2B,LEF1,ESR1,NKX3-1,NKX3,ESR2A,GPR30 |
| enzyme binding | DAOA,DYM,PRTN3,SPDL1,UGT1A2,HIST1H2AG,MLEC,LDB2,NOXO1,CFTR |
| core promoter sequence-specific DNA binding | GATA3,ESR1,SOX4,MTA1,RORA,SOX1,CREM,TOP1,NFYA,SOX9 |
Interacting Protein
ESR2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ESR2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ESR2.
RPS18;RPS4X;RPS26;PTCD3;MYLK2;PLSCR1;ESR1
Resources
Research Area
Transcription Regulators in VSMCCancer Stem Cell Transcription Factors
Cancer Biomarkers in Clinical Practice
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References
