EFNB1
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Official Full Name
ephrin-B1 -
Overview
The protein encoded by this gene is a type I membrane protein and a ligand of Eph-related receptor tyrosine kinases. It may play a role in cell adhesion and function in the development or maintenance of the nervous system. -
Synonyms
EFNB1;ephrin-B1;CFNS, craniofrontonasal syndrome (craniofrontonasal dysplasia) , EPLG2;Elk L;LERK2;CFND;CFNS;Craniofrontonasal syndrome (craniofrontonasal dysplasia);EFL 3;EFL-3;EFL3;EFNB1_HUMAN;ELK ligand;ELK-L;Eph related receptor tyrosine kinase ligand 2;EPH-related receptor tyrosine kinase ligand 2;EPLG2;LERK 2;LERK-2;Ligand of eph related kinase 2;MGC8782;OTTHUMP00000023456;ligand of eph-related kinase 2
Recombinant Proteins
- Human
- Mouse
- Rat
- Rhesus macaque
- Chicken
- Zebrafish
- Xenopus laevis
- Mus musculus
- HEK293
- Human Cells
- Insect Cells
- E.coli
- Mammalian Cells
- Wheat Germ
- Human
- In Vitro Cell Free System
- His
- Fc&His
- Fc
- Non
- GST
- Avi&Fc&His
- DDK&Myc
- His&Strep
Involved Pathway
EFNB1 involved in several pathways and played different roles in them. We selected most pathways EFNB1 participated on our site, such as Axon guidance,Developmental Biology,EPH-Ephrin signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with EFNB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| EPH-Ephrin signaling | EFNB3,SDCBP,EPHB3A,EFNA2,EFNA4,AP2M1,EFNA5,AP2A2,ACTR3,ARPC3 |
| EPH-ephrin mediated repulsion of cells | EFNB2,EFNA1B,EFNA2A,EPHA2,EPHB4B,EPHA2A,EPHB3A,EFNA1,EPHA10,AP2A2 |
| Ephrin B reverse signaling | PTPN13,EFNB2 |
| Ephrin signaling | EFNB3,EPHB4A,EPHB3A,SDCBP,EPHB4B,EFNB2,EFNB3B,MYL12A,EFNB2A |
| Axon guidance | PTK2,SLC14A2,PAK4,EFNA1A,EFNB2A,MYL12B,EPHA7,EPHB6,CDK5R1B,NTN4 |
| EPHB forward signaling | EFNB2,ITSN1,EFNB3,GRB7,EFNA5 |
| EPHB-mediated forward signaling | EFNB2,EFNB3B,KALRN,KALRNB,ACTR2B,ARPC5,ARPC2,EFNB3,ARPC4,EPHB4B |
| Developmental Biology | CRMP1,DUSP10,MYL12A,SIAH2,DCC,NRG2A,LGI2A,PAQR3A,JAK1,EPHA2 |
Protein Function
EFNB1 has several biochemical functions, for example, ephrin receptor binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EFNB1 itself. We selected most functions EFNB1 had, and list some proteins which have the same functions with EFNB1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | MTAP1B,SF3B2,ARL8A,DIABLO,ID2,ATG14,KREMEN1,PIH1D1,SLC9A3R1,BAX |
| ephrin receptor binding | SIPA1L1,EPHA7,EFNB2A,PTPN1,EFNA5,EFNA1B,EFNB2B,EFNA4,NTRK3,Anks1 |
Interacting Protein
EFNB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EFNB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of EFNB1.
ERBB2;Erbb2;Sdcbp;MYC;YWHAQ;CUL3;Pick1;Grip1;CAPN10
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