DHX9

  • Official Full Name

    DEAH (Asp-Glu-Ala-His) box polypeptide 9

  • Overview

    This gene encodes a member of the DEAH-containing family of RNA helicases. The encoded protein is an enzyme that catalyzes the ATP-dependent unwinding of double-stranded RNA and DNA-RNA complexes. This protein localizes to both the nucleus and the cytoplasm and functions as a transcriptional regulator. This protein may also be involved in the expression and nuclear export of retroviral RNAs. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 11 and 13.

  • Synonyms

    DHX9;DEAH (Asp-Glu-Ala-His) box polypeptide 9;DDX9, DEAD/H (Asp Glu Ala Asp/His) box polypeptide 9 (RNA helicase A, nuclear DNA helicase II;leukophysin) , LKP;ATP-dependent RNA helicase A;NDH II;RHA;leukophysin;DEAH box protein 9;nuclear DNA hel

Recombinant Proteins

  • Rhesus macaque
  • Human
  • Mouse
  • Zebrafish
  • Mammalian Cell
  • Wheat Germ
  • E.coli
  • E.Coli or Yeast
  • HEK293
  • E. coli
  • Baculovirus infected insect cells
  • His
  • Non
  • His&SUMO
  • Flag&Myc
  • GST
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
DHX9-1264R Recombinant Rhesus monkey DHX9 Protein, His-tagged Mammalian Cell Rhesus macaque His
DHX9-30765TH Recombinant Human DHX9 Wheat Germ Human Non 90 amino acids
DHX9-32H Recombinant Human DHX9 protein, His/SUMO-tagged E.coli Human His&SUMO 325-840 a.a.
Dhx9-3749M Recombinant Mouse Dhx9, His-tagged E.Coli or Yeast Mouse His 1383
DHX9-4586M Recombinant Mouse DHX9 Protein Mammalian Cell Mouse His
DHX9-630H Recombinant Human DHX9 protein, Flag-Myc-tagged HEK293 Human Flag&Myc 325-840aa
DHX9-631H Recombinant Human DHX9 protein, GST-tagged Wheat Germ Human GST 1 a.a. - 90 a.a.
DHX9-7932Z Recombinant Zebrafish DHX9 Mammalian Cell Zebrafish His
DHX9-1089R Recombinant Rhesus Macaque DHX9 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
DHX9-1089R-B Recombinant Rhesus Macaque DHX9 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
DHX9-10H Recombinant Human DHX9 Protein, His tagged E. coli Human His 100-330 aa
DHX9-12H Active Recombinant Human DHX9 Protein, His tagged Baculovirus infected insect cells Human His 150-1270 aa
DHX9-2372M Recombinant Mouse DHX9 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
DHX9-2372M-B Recombinant Mouse DHX9 Protein Pre-coupled Magnetic Beads HEK293 Mouse
DHX9-33H Recombinant Human DHX9 protein, His-tagged E.coli Human His 325-840aa

    Involved Pathway

    DHX9 involved in several pathways and played different roles in them. We selected most pathways DHX9 participated on our site, such as Activated TLR4 signalling,Cytosolic sensors of pathogen-associated DNA,DEx/H-box helicases activate type I IFN and inflammatory cytokines production, which may be useful for your reference. Also, other proteins which involved in the same pathway with DHX9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytosolic sensors of pathogen-associated DNA CRCP,TICAM1,SAA1,APPA,TRIM56,RIPK3,APPB,NLRP4C,S100B,NLRP4B
    MyD88 cascade initiated on plasma membrane PELI1,TNIP2,AGER,DUSP3B,PELI2,CHST13,TLR10,S100B,PELI3,ALCAMB
    MyD88 dependent cascade initiated on endosome S100B,ALCAMB,CHST13,S100A12
    Gene Expression NR2F1,RNF111,GATAD2A,ZFP90,USP9,NR1H3,HENMT1,ZNF473,ZNF557,C22orf28
    Activated TLR4 signalling PELI3,DUSP6,AGER,SAA1,S100B,MAPKAPK2B,DUSP3,NOD1,MAP3K8,MAPK14
    Immune System NCKIPSD,CD300C,CFHL1,STIM1B,GRAP2A,TREX1,PPAPDC1B,TRIM45,ASB10,TXN
    Innate Immune System CLEC6A,DEFB121,POLR3C,CYLD,PANX1A,CFHL1,DEFB119,CTS7,CR1,SIRPB1
    DEx/H-box helicases activate type I IFN and inflammatory cytokines production APPA,CHST13,AGER,SAA1,ALCAMB,S100A12,APPB,S100B

    Protein Function

    DHX9 has several biochemical functions, for example, ATP binding,ATP-dependent DNA helicase activity,ATP-dependent RNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DHX9 itself. We selected most functions DHX9 had, and list some proteins which have the same functions with DHX9. You can find most of the proteins on our site.

    Function Related Protein
    RNA helicase activity DHX15,DDX6,DHX16,DDX17,DDX24,CTU1,FAM120B,CCDC111,CHST13,PRIM2
    RNA polymerase II transcription factor binding KLF4,XBP1,ZGLP1,HCLS1,ZFPM2,MTA2,GATA1,ANKRD1,MTDH,TBX6
    ATP-dependent DNA helicase activity RTEL1,BLM,ERCC2,G3BP1,BRIP1,RUVBL2,CHD1,CHD2,GTF2H4,DDX3X
    DNA binding FOXO6,THAP5,GFI1B,HIST2H3C,ENG1A,TBX10,HIST1H4I,POU2F1A,ZFP367,UBN2A
    protein binding NGDN,TRAPPC6B,SGSM3,CST1,CSRP2,TUBA3D,C9orf43,AP2A2,RTP4,ELMO3
    ATP-dependent RNA helicase activity DDX3,DDX59,DDX27,DDX4,DHX32,DDX25,DHX8,DDX55,DDX54,DHX38
    poly(A) RNA binding MRTO4,NSBP1,DMGDH,NXF2,PEBP1,MYH9,RBM26,G3BP1,MKI67IP,SRSF12
    ATP binding GALK2,PRPF4B,PIP4K2B,SETX,CDK17,GAK,PAK2A,CASK,KIF16B,MAPK10

    Interacting Protein

    DHX9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DHX9 here. Most of them are supplied by our site. Hope this information will be useful for your research of DHX9.

    NXF1;YBX1;cte_mpmv

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