DAPK2

  • Official Full Name

    death-associated protein kinase 2

  • Overview

    This gene encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis.It uses multiple polyadenylation sites.

  • Synonyms

    DAPK2;death-associated protein kinase 2;DRP 1;MGC119312;DAP kinase 2;DAP-kinase-related protein 1 beta isoform;DRP1;DRP-1

Recombinant Proteins

  • Human
  • Mouse
  • Wheat Germ
  • Sf9 Cells
  • Mammalian Cells
  • Insect Cells
  • HEK293
  • E.coli
  • GST
  • Non
  • His
  • DDK&Myc
  • Avi&Fc&His
Cat.# Product name Source (Host) Species Tag Protein Length Price
DAPK2-2339H Recombinant Human DAPK2 Protein, GST-tagged Wheat Germ Human GST
DAPK2-26805TH Recombinant Human DAPK2 Human Non Full L. 1-370 a.a.
DAPK2-290H Recombinant Human DAPK2, GST-tagged, Active Sf9 Cells Human GST
DAPK2-4305M Recombinant Mouse DAPK2 Protein Mammalian Cells Mouse His
DAPK2-675H Recombinant Human Death-Associated Protein Kinase 2, His-tagged Insect Cells Human His Full L.
DAPK2-7076HCL Recombinant Human DAPK2 293 Cell Lysate HEK293 Human Non
DAPK2-1237H Recombinant Human DAPK2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
DAPK2-1311H Recombinant Human DAPK2 Protein, His-tagged E.coli Human His Met1-Thr235
DAPK2-2201M Recombinant Mouse DAPK2 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
DAPK2-2201M-B Recombinant Mouse DAPK2 Protein Pre-coupled Magnetic Beads HEK293 Mouse
Dapk2-2452M Recombinant Mouse Dapk2 Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc

    Involved Pathway

    DAPK2 involved in several pathways and played different roles in them. We selected most pathways DAPK2 participated on our site, such as Pathways in cancer,Bladder cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with DAPK2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Bladder cancer MAPK1,MYC,UPK3A,MDM2,IL-8,CDH1,HRAS,NRAS,MMP1A,E2F2
    Pathways in cancer AXIN2,LAMA3,TRAF2,MTOR,TCF7L2,GSK3B,FN1,RAC2,GNG2,NKX3-1

    Protein Function

    DAPK2 has several biochemical functions, for example, ATP binding,calmodulin binding,identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DAPK2 itself. We selected most functions DAPK2 had, and list some proteins which have the same functions with DAPK2. You can find most of the proteins on our site.

    Function Related Protein
    protein serine/threonine kinase activity STK4,OXSR1A,CSNK2A1,PKN1B,PRKCE,STK30,NEK3,MAP4K3,GRK7B,BMPR1BA
    identical protein binding ETNPPL,NQO1,DNMT3A,NUP153,FAS,ROBO1,COL7A1,EPHA4,ST13,VPS41
    ATP binding ADK,SWAP70,GUCY2F,HSPH1,Ckmm,UBE2S,IP6K1,TEK,ABCG2C,DDX28
    protein binding GADD45GIP1,TRIM33,REL,SNX7,IDE,GNB2L1,EEF2,PCSK9,SNAP47,TRIM6
    calmodulin binding RIT1,PHKG1,MAP2,SNTA1,CAMK1GA,MKNK2,NOS1,RGS2,TRPM4,KCNH1

    Interacting Protein

    DAPK2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DAPK2 here. Most of them are supplied by our site. Hope this information will be useful for your research of DAPK2.

    FAM9B;Bub1;LLGL2;KLC3;TUBGCP5;RACGAP1

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