D2hgdh
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Official Full Name
D-2-hydroxyglutarate dehydrogenase
Recombinant Proteins
- Mouse
- Zebrafish
- Human
- zebrafish
- Mammalian Cell
- HEK293
- E.coli
- Yeast
- Mammalian cells
- HEK293T
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&SUMO
- His&T7
- Flag
- His&Fc&Avi
- Myc&DDK
- GST
Involved Pathway
D2hgdh involved in several pathways and played different roles in them. We selected most pathways D2hgdh participated on our site, such as Interconversion of 2-oxoglutarate and 2-hydroxyglutarate,Metabolism,Pyruvate metabolism and Citric Acid (TCA) cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with D2hgdh were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolism | IVD,SULT1B1,ARF3,ABHD10,PITPNB,ECI1,PTGDSA,PMVK,FAM36A,ACY3.1 |
| The citric acid (TCA) cycle and respiratory electron transport | NDUFAF3,PDK4,NDUFAF4,ATP5S,FAM36A,ETFB,COX16,NDUFAF6,C2orf56,NDUFAF7 |
| Pyruvate metabolism and Citric Acid (TCA) cycle | PDK3,PDPR,SLC16A8,PDK2,PDK4,PDK2B,ADHFE1,SLC16A1,PDK3B,BRP44 |
| Interconversion of 2-oxoglutarate and 2-hydroxyglutarate | ADHFE1 |
Protein Function
D2hgdh has several biochemical functions, for example, (R)-2-hydroxyglutarate dehydrogenase activity,flavin adenine dinucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by D2hgdh itself. We selected most functions D2hgdh had, and list some proteins which have the same functions with D2hgdh. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| (R)-2-hydroxyglutarate dehydrogenase activity | HSD11B1LA,HSD3B5,SDR42E1,HSD3B6,AKR1C6,SDR16C6,AKR1C21,H2-KE6 |
| flavin adenine dinucleotide binding | DUS4L,MTO1,KDM1B,NOX4,CYBB,SDHA,PPOX,FMO3,GULO,DLD |
Interacting Protein
D2hgdh has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with D2hgdh here. Most of them are supplied by our site. Hope this information will be useful for your research of D2hgdh.
RAB25;STK11
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References
- Chen, R; Ravindra, VM; et al. Molecular features assisting in diagnosis, surgery, and treatment decision making in low-grade gliomas. NEUROSURGICAL FOCUS 38:-(2015).
- Hirata, M; Sasaki, M; et al. Mutant IDH is sufficient to initiate enchondromatosis in mice. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 112:2829-2834(2015).
