CLEC4D
-
Official Full Name
C-type lectin domain family 4, member D -
Overview
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. -
Synonyms
CLEC4D;C-type lectin domain family 4, member D;C type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 8 , CLECSF8;C-type lectin domain family 4 member D;Mpcl;C type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 8;C type lectin domain family 4, member D;C type lectin like receptor 6;C type lectin receptor;C type lectin superfamily member 8;CLEC 6;CLEC6;CLECSF8;Macrophage C type lectin;MCL;MGC40078;C-type lectin receptor;macrophage C-type lectin;C-type lectin-like receptor 6;C-type lectin superfamily member 8;C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 8;CLEC-6
Recombinant Proteins
- Human
- Rat
- Rhesus macaque
- Mouse
- HEK293
- Mammalian Cell
- Wheat Germ
- Human Cell
- Rabbit
- E.coli
- In Vitro Cell Free System
- HEK293T
- His
- GST
- Fc
- Non
- His&SUMO
- His&Fc&Avi
- Myc&DDK
Involved Pathway
CLEC4D involved in several pathways and played different roles in them. We selected most pathways CLEC4D participated on our site, such as C-type lectin receptors (CLRs),Dectin-2 family,Immune System, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLEC4D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Dectin-2 family | CLEC6A,CLEC4A |
| C-type lectin receptors (CLRs) | MALT1,AHCYL1,TAB1,IL1B2,CREBBP,CASP8L1,CLEC4A,ITPR2,UBE2V1,CLEC6A |
| Immune System | PPAPDC1A,KPNA3,MGC174155,CD200R3,ASB14,AP1S3A,LAIR2,LTF,POLR3C,LILRB3 |
| Innate Immune System | NLRP4,RCA2.1,BTR12,ACTR2B,KIR3DS1,SIGLEC15,ABI1B,BAIAP2,PELI3,NCKIPSD |
Protein Function
CLEC4D has several biochemical functions, for example, carbohydrate binding,immunoglobulin receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CLEC4D itself. We selected most functions CLEC4D had, and list some proteins which have the same functions with CLEC4D. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| carbohydrate binding | HBL4,CLEC18B,NPTX2,ZG16B,SIGLEC9,CD248,CDIPT,CLEC6A,GALNT4,REG3A |
| immunoglobulin receptor binding | Ighg2a,IGKC,IgG3,FES,IGLL1,Ighg2b,FGR,Ighg,IGLC2 |
Interacting Protein
CLEC4D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLEC4D here. Most of them are supplied by our site. Hope this information will be useful for your research of CLEC4D.
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