CDC42EP2
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Official Full Name
CDC42 effector protein (Rho GTPase binding) 2 -
Overview
CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of CDC42. Coexpression of this protein with CDC42 suggested a role of this protein in actin filament assembly and cell shape control. -
Synonyms
CDC42EP2;CDC42 effector protein (Rho GTPase binding) 2;cdc42 effector protein 2;BORG1;CEP2;CRIB containing BOGR1 protein;Binder of Rho GTPases 1;CRIB-containing BOGR1 protein;OTTHUMP00000231608
Recombinant Proteins
- Human
- Rat
- Zebrafish
- Mouse
- Rhesus macaque
- Wheat Germ
- Mammalian Cell
- HEK293
- HEK293T
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
CDC42EP2 involved in several pathways and played different roles in them. We selected most pathways CDC42EP2 participated on our site, such as MAPK family signaling cascades,MAPK6/MAPK4 signaling,Signal Transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDC42EP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| MAPK family signaling cascades | MAPK4,CDC42EP1B,MAPK6,CDC42EP5,IGF2BP1,SEPT7,CDC42EP3 |
| MAPK6/MAPK4 signaling | SEPT7,CDC42EP3,CDC42EP5,CDC42EP1B,IGF2BP1,MAPK4,MAPK6 |
| Signal Transduction | GPRC6A,ARHGAP22,ROR2,SOX6,GAL,ARHGAP18,CRHB,OR56A1,GRB10A,USP9X |
Protein Function
CDC42EP2 has several biochemical functions, for example, GTP-Rho binding,GTPase activator activity,opioid peptide activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CDC42EP2 itself. We selected most functions CDC42EP2 had, and list some proteins which have the same functions with CDC42EP2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTP-Rho binding | RTKN,ROCK2A,CDC42EP1B,ROCK2B,ROCK1,EXOC1,KCTD13,TNFAIP1,PKN1,WHAMM |
| GTPase activator activity | ECT2,ARHGAP4A,THY1,RGS10,RGS5A,AGFG1A,RGS14,RGS12,TIAM2,RGS9A |
| protein binding | KLRB1F,WSB1,SORBS3,CEBPA,CLEC4G,CHN1,TBP,KDM1A,CEP57,UBE4A |
| opioid peptide activity | PNOC,PENK,PDYN,ZFP106 |
Interacting Protein
CDC42EP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDC42EP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDC42EP2.
CDC42;ARHGAP26;NME7
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