CDC20
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Official Full Name
cell division cycle 20 homolog (S. cerevisiae) -
Overview
CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. It is required for two microtubule-dependent processes, nuclear movement prior to anaphase and chromosome separation. -
Synonyms
CDC20;cell division cycle 20 homolog (S. cerevisiae);CDC20A;p55CDC;MGC102824;bA276H19.3;cell division cycle protein 20 homolog;OTTHUMP00000008571;OTTHUMP00000008572;CDC20 cell division cycle 20 homolog;Cdc 20;fizzy
Recombinant Proteins
- Human
- Zebrafish
- Rat
- Chicken
- Rhesus macaque
- Mouse
- Wheat Germ
- Mammalian Cells
- HEK293
- In Vitro Cell Free System
- E.coli
- GST
- His
- Non
- Myc&DDK
- Flag
- His&Fc&Avi
- His&Myc
Involved Pathway
CDC20 involved in several pathways and played different roles in them. We selected most pathways CDC20 participated on our site, such as Cell cycle,Oocyte meiosis,Ubiquitin mediated proteolysis, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDC20 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ubiquitin mediated proteolysis | BIRC7,BRCA1,CDC34,BIRC2,FBXW11,ANAPC7,UBA2,UBR5,VHL,CUL3B |
| Oocyte meiosis | CUL1A,CCNB2,PLCZ1,PPP3CA,PPP2R5D,RPS6KAL,MAP2K1,PPP2R5B,MAPK12,PPP2R5C |
| Viral carcinogenesis | HIST1H4A,CREB3L3,RELA,HIST1H2BQ,DNAJA3,RBL2,HDAC11,HDAC1,HIST1H2BC,SCRIB |
| Cell cycle | MAD1L1,CDK1,MIS18BP1,MCM3,ORC5,GADD45G,ANAPC7,ITGB3BP,CDC14AA,TGFB2 |
| HTLV-I infection | ELK1,WNT6,ITGAL,BCL2L1,IKBKB,CRTC2,VDAC3,IL2RA,NRP1,ANAPC5 |
Protein Function
CDC20 has several biochemical functions, for example, enzyme binding,histone deacetylase binding,protein C-terminus binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDC20 itself. We selected most functions CDC20 had, and list some proteins which have the same functions with CDC20. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein C-terminus binding | CORO1A,PXK,GRIP1,ABL1,VTA1,BAIAP2,ID1,SIAH1A,SLC4A1,AP2A1 |
| protein binding | TNNI2,PTPRJ,NCF1,MATR3,ZKSCAN4,RUSC1,BCL2,ITGAX,PLEKHG2,TNFRSF12A |
| enzyme binding | POLB,UGT1A9,NPC2,TULP3,HDAC2,HSPA1A,CPSF1,BTG1,APOA5,CD40 |
| histone deacetylase binding | TAL1,SP2,RELA,RBBP4,NRIP1,ZNF703,HDAC4,RAD9A,HDAC10,CBX5 |
Interacting Protein
CDC20 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDC20 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDC20.
BUB1B;MAD2L1
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References
- Lu, L; Hu, SH; et al. The HECT Type Ubiquitin Ligase NEDL2 Is Degraded by Anaphase-promoting Complex/Cyclosome (APC/C)-Cdh1, and Its Tight Regulation Maintains the Metaphase to Anaphase Transition. JOURNAL OF BIOLOGICAL CHEMISTRY 288:35637-35650(2013).
- Petra, H; Eva, H; et al. Molecular Profiling of Acute and Chronic Rejections of Renal Allografts. CLINICAL & DEVELOPMENTAL IMMUNOLOGY :-(2013).
