CALCB
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Official Full Name
calcitonin-related polypeptide beta -
Synonyms
CALCB;calcitonin-related polypeptide beta;CALC2, calcitonin 2;calcitonin gene-related peptide 2;CGRP II;FLJ30166;Beta type CGRP;CALC2;Calcitonin gene related peptide 2;Calcitonin gene related peptide II;Calcitonin related polypeptide, beta;CGRP2;CGRPII;beta-CGRP;calcitonin 2;beta-type CGRP;calcitonin gene-related peptide II;CGRP-II
Recombinant Proteins
- Human
- Rat
- Mouse
- Wheat Germ
- Mammalian Cell
- Human Cell
- E.coli
- HEK293
- In Vitro Cell Free System
- HEK293T
- GST
- His
- Non
- Myc&DDK
- mFc
- His&GST
- His&Fc&Avi
Involved Pathway
CALCB involved in several pathways and played different roles in them. We selected most pathways CALCB participated on our site, such as Calcitonin-like ligand receptors,Class B/2 (Secretin family receptors),G alpha (s) signalling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with CALCB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Calcitonin-like ligand receptors | ADM2A,RAMP1,CALCRL,RAMP3,CALCA,ADM,RAMP2,ADM2 |
| GPCR downstream signaling | LTB4R,ABR,SSTR3,PRKCHB,PROKR2,CHRM2,ADORA2A,PMCH,CALCRL,HCAR1-2 |
| G alpha (s) signalling events | PTHLHA,RLN3A,PTH,RAMP1,CGA,ADM2,VIP2,RXFP2B,CALCA,NPSR1 |
| Signal Transduction | XK,CRHR2,WLS,ARHGAP36,ARHGEF3,CHN2,ARHGAP29,ARHGEF25,USP2,DLK1 |
| GPCR ligand binding | CCRL2,LTB4R,MLN,GPR68,PROKR1,UTS2D,NMBB,PROKR1A,GHRH,NMS |
| Class B/2 (Secretin family receptors) | CRHR2,SCT,CRH,RAMP3,ADCYAP1R1,CRHR1,ADM2,CD97,ADCYAP1,GNB5A |
| Signaling by GPCR | RGS1,SCT,OR2AP1,PNOCB,GPR120,NET1,TAS2R16,ARHGAP4,FGD4,KEL |
Protein Function
CALCB has several biochemical functions, for example, neuropeptide hormone activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CALCB itself. We selected most functions CALCB had, and list some proteins which have the same functions with CALCB. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| neuropeptide hormone activity | C12orf39,CCK,NPY,NPFF,AGRP,UCN,GRP,PRLH,CRH,VIP |
Interacting Protein
CALCB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CALCB here. Most of them are supplied by our site. Hope this information will be useful for your research of CALCB.
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References
- Baisley, SK; Bremer, QZ; et al. Antipsychotic-Like Actions of the Satiety Peptide, Amylin, in Ventral Striatal Regions Marked by Overlapping Calcitonin Receptor and RAMP-1 Gene Expression. JOURNAL OF NEUROSCIENCE 34:4318-4325(2014).
- Murrills, RJ; Fukayama, S; et al. Osteogenic Effects of a Potent Src-over-Abl-Selective Kinase Inhibitor in the Mouse. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 340:676-687(2012).
