BCAT2
-
Official Full Name
branched chain amino-acid transaminase 2, mitochondrial -
Overview
This gene encodes a branched chain aminotransferase found in mitochondria. The encoded protein forms a dimer that catalyzes the first step in the production of the branched chain amino acids leucine, isoleucine, and valine. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
BCAT2;branched chain amino-acid transaminase 2, mitochondrial;BCT2, branched chain aminotransferase 2, mitochondrial;branched-chain-amino-acid aminotransferase, mitochondrial;BCAM;mitochondrial;BCAT 2;BCAT(m);BCAT2_HUMAN;BCATM;BCT2;Branched chain aminotransferase 2, mitochondrial;Branched-chain-amino-acid aminotransferase;ECA40;Placental protein 18;PP18
Recombinant Proteins
- Human
- Rat
- Zebrafish
- Mouse
- E.coli
- Wheat Germ
- Mammalian Cell
- In Vitro Cell Free System
- HEK293
- Mammalian cells
- HEK293T
- His
- His&T7
- GST
- Non
- His&Strep
- Myc&DDK
- His&Myc
- His&SUMO
- His&Fc&Avi
- Flag
Involved Pathway
BCAT2 involved in several pathways and played different roles in them. We selected most pathways BCAT2 participated on our site, such as Cysteine and methionine metabolism,Valine, leucine and isoleucine degradation,Valine, leucine and isoleucine biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with BCAT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Valine, leucine and isoleucine degradation | BCKDHA,ALDH3A2,ALDH9A1,MCEE,HIBADH,HMGCLL1,MCCC1,ALDH7A1,AOX3L1,HADHA |
| -Oxocarboxylic acid metabolism | ACO1,IDH1,GOT2A,IDH3G,ACY1,GOT2,IDH3A,GPT2L,GPT2,ACO2 |
| Pantothenate and CoA biosynthesis | PPCDC,VNN2,UPB1,PANK2,DPYS,PANK3,ENPP1,PPCS,PANK4,DPYDB |
| Biosynthesis of amino acids | PYCR2,PSPH,pykF,BCAT1,ALDOB,SDS,MAT2AL,TKTL1,MAT2A,GLULC |
| Metabolic pathways | DCTPP1,FAM213B,EPHX2,RGN,DHCR24,AMPD2,CKMT1,ADH1C,ATP5J2,HADHB |
| Valine, leucine and isoleucine biosynthesis | BCAT1 |
| Cysteine and methionine metabolism | SMS,SDS,MTR,GCLC,AGXT2,GOT1,LDHBB,LDHB,TAT,CBSA |
Protein Function
BCAT2 has several biochemical functions, for example, L-isoleucine transaminase activity,L-leucine transaminase activity,L-valine transaminase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by BCAT2 itself. We selected most functions BCAT2 had, and list some proteins which have the same functions with BCAT2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| branched-chain-amino-acid transaminase activity | BCAT1 |
| L-isoleucine transaminase activity | BCAT1 |
| L-valine transaminase activity | BCAT1 |
| L-leucine transaminase activity | BCAT1 |
Interacting Protein
BCAT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BCAT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of BCAT2.
CREB3;ALDOA;PTGDS
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