ASH2L

  • Official Full Name

    ash2 (absent, small, or homeotic)-like

  • Overview

    Set1/Ash2 histone methyltransferase complex subunit ASH2 is an enzyme that in humans is encoded by the ASH2L gene.

  • Synonyms

    ASH2L;ash2 (absent, small, or homeotic)-like (Drosophila);ash2 (absent, small, or homeotic, Drosophila, homolog) like , ASH2L1;set1/Ash2 histone methyltransferase complex subunit ASH2;ASH2;ASH2L2;Bre2;ASH2-like protein;ASH2L1

Recombinant Proteins

  • Human
  • Chicken
  • Zebrafish
  • Mouse
  • E.coli
  • Mammalian Cell
  • Wheat Germ
  • HEK293
  • In Vitro Cell Free System
  • HEK293T
  • E. coli
  • GST
  • SUMO
  • His
  • Non
  • His&SUMO
  • Myc&DDK
Cat.# Product name Source (Host) Species Tag Protein Length Price
ASH2L-9933H Recombinant Human ASH2L, GST-tagged E.coli Human GST C-term-300a.a.
ASH2L-009H Active Recombinant Human ASH2L Protein, SUMO-tagged E.coli Human SUMO 96-628
ASH2L-3046C Recombinant Chicken ASH2L Mammalian Cell Chicken His
ASH2L-6103Z Recombinant Zebrafish ASH2L Mammalian Cell Zebrafish His
ASH2L-906H Recombinant Human ASH2L protein, GST-tagged Wheat Germ Human GST
ASH2L-8652HCL Recombinant Human ASH2L 293 Cell Lysate HEK293 Human Non
ASH2L-1087HF Recombinant Full Length Human ASH2L Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 534 amino acids
ASH2L-1146H Recombinant Human ASH2L Protein (1-534 aa), His-SUMO-tagged E.coli Human His&SUMO 1-534 aa
ASH2L-159H Recombinant Human ASH2L Protein, SUMO-tagged E.coli Human SUMO
Ash2l-1743M Recombinant Mouse Ash2l Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
ASH2L-25HFL Recombinant Human ASH2L Protein, Full Length, N-GST tagged E. coli Human GST Full L. Full Length
ASH2L-30HFL Recombinant Human ASH2L Protein, Full Length, N-His tagged E. coli Human His Full L. Full Length

    Involved Pathway

    ASH2L involved in several pathways and played different roles in them. We selected most pathways ASH2L participated on our site, such as Chromatin modifying enzymes,Chromatin organization,Deactivation of the beta-catenin transactivating complex, which may be useful for your reference. Also, other proteins which involved in the same pathway with ASH2L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Chromatin organization MSL2A,ARID2,KDM4C,CSRP2BP,SMARCB1A,EED,ING5B,PBRM1,ATF7IP,ATXN7L3
    Chromatin modifying enzymes RBBP4,ZZZ3,DNMT3A,SMARCB1B,PADI2,DR1,ARID2,MTA1,NCOA2,MORF4L2
    PKMTs methylate histone lysines SMYD2,ATF7IP,AEBP2,RBBP5,EHMT2,SUZ12B,SMYD2A,DPY30,SETD3,SMYD3
    Signaling by Wnt CCDC88C,SOX4B,PYGO1,RNF43,RSPO2,LEO1,SOX6,HECW1,RSPO4,LGR5
    Formation of the beta-catenin:TCF transactivating complex TLE3B,H3F3B.1,RBBP5,BCL9L,TLE3,H3F3D,PYGO1,PYGO2,TLE4,TLE1
    Deactivation of the beta-catenin transactivating complex TLE4,RBBP5,TLE1,CBY1,SOX32,SOX4A,TLE2,SOX4B,PYGO1,TLE3
    Signal Transduction LPAR2B,PDK2B,MDKA,TNKS,TAX1BP1,ARHGEF18,SOUL3,RGS14,FMNL2,DTX2
    TCF dependent signaling in response to WNT KREMEN1,BCL9L,WIF1,SOX9A,PYGO2,LGR5,CBY1,CCDC88C,C,WNT8-2

    Protein Function

    ASH2L has several biochemical functions, for example, DNA binding,beta-catenin binding,euchromatin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ASH2L itself. We selected most functions ASH2L had, and list some proteins which have the same functions with ASH2L. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding TEAD2,ZFP628,ZNF80,SIX2B,ESRRA,HIST3H2BB,ONECUTL,FOXP1B,ZNF280B,TMF1
    beta-catenin binding BCL9,HDAC6,SLC9A3R1,CXADR,KDM6B,SALL1,CD2AP,AXIN2,GSK3B,APC
    euchromatin binding CTNNB1
    transcription regulatory region DNA binding IKZF2,TBX21,TBL1X,NKX2,BCOR,HNRNPL,LEF1,YAP1,BRCA1,HMGB2
    protein binding IL1RAPL1,PIK3CB,NKX2-5,THEM5,UBXN8,PDZK1,STAC3,SPTA1,MNDA,PAG1
    metal ion binding TRIM35-28,ATP13A4,ZNF580,ZNF354B,ZDHHC1,MIPEP,TRIM35-29,EXTL3,PPP1CC,SRSF7A
    contributes_to histone methyltransferase activity (H3-K4 specific) DYDC2,CXXC1,RBBP5,DYDC1,DPY30

    Interacting Protein

    ASH2L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ASH2L here. Most of them are supplied by our site. Hope this information will be useful for your research of ASH2L.

    RBBP5;DPY30

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