AHNAK
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Official Full Name
AHNAK nucleoprotein -
Overview
Neuroblast differentiation-associated protein AHNAK, also known as desmoyokin, is a protein that in humans is encoded by the AHNAK gene. AHNAK was originally identified in 1989 (in bovine muzzle epidermal cells) and named desmoyokin due to its localization pattern (that resembled a yoke) in the desmosomal plaque. AHNAK has been shown to be essential for pseudopod protrusion and cell migration. -
Synonyms
AHNAK;AHNAK nucleoprotein;AHNAK nucleoprotein (desmoyokin);neuroblast differentiation-associated protein AHNAK;desmoyokin;AHNAK-related;MGC5395;PM227;AHNAKRS;OTTHUMP00000236155;OTTHUMP00000236448;OTTHUMP00000236450;OTTHUMP00000236451;Desmoyokin
Recombinant Proteins
- Human
- Mouse
- Wheat Germ
- HEK293
- E. coli
- E.coli
- Mammalian cells
- HEK293T
- In Vitro Cell Free System
- GST
- Non
- N-His and C-His
- His
- Flag
- Myc&DDK
- His&T7
- His&Fc&Avi
Involved Pathway
AHNAK involved in several pathways and played different roles in them. We selected most pathways AHNAK participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with AHNAK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
AHNAK has several biochemical functions, for example, S100 protein binding,poly(A) RNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AHNAK itself. We selected most functions AHNAK had, and list some proteins which have the same functions with AHNAK. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | PPIL4,DHX29,C1orf131,CSNK1E,RPS27.1,ZNFX1,RPUSD4,ZFP36L1,DYNC1H1,HSPA8 |
| protein binding | SPDYE2,KLK13,NR4A3,NUDT21,EFCAB12,KCNE1L,MEP1B,ERP27,GP1BB,PTI |
| structural molecule activity conferring elasticity | TTN |
| S100 protein binding | S100A11,KCNK3,S100A6,S100B,FGF1,ANXA11,FGF1A,DDX1,AGER,ATP2A2 |
Interacting Protein
AHNAK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AHNAK here. Most of them are supplied by our site. Hope this information will be useful for your research of AHNAK.
EGFR;Anxa2;S100A10;YWHAZ;Tpr;Bles03;Csnk1e;p27958-pro_0000037576;fopA1;acnA;q7cfv5_yerpe;pz-A;POT1;1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate;pi3p;midostaurin
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References
- Yao, J; Ong, SE; et al. Huntingtin is associated with cytomatrix proteins at the presynaptic terminal. MOLECULAR AND CELLULAR NEUROSCIENCE 63:96-100(2014).
- Lim, HJ; Kang, DH; et al. Function of Ahnak protein in aortic smooth muscle cell migration through Rac activation. CARDIOVASCULAR RESEARCH 97:302-310(2013).
