ZNRF3
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Official Full Name
zinc and ring finger 3 -
Synonyms
ZNRF3;zinc and ring finger 3;18126;ENSG00000183579;RNF203;BK747E2.3;22q12.1;E3 ubiquitin-protein ligase ZNRF3;E3 ubiquitin-protein ligase ZNRF3;RING finger protein 203;zinc/RING finger protein 3;novel C3HC4 type Zinc finger (ring finger);EC 6.3.2.-
Recombinant Proteins
- Mouse
- Human
- Mouse myeloma cell line
- Mammalian Cell
- HEK293
- Yeast
- Insect Cell
- E.coli
- Fc
- His
- His&Fc&Avi
- His&SUMO
- Non
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Znrf3-33M |
Active Recombinant Mouse zinc and ring finger 3 protein, Fc tagged
|
Mouse myeloma cell line | Mouse | Fc | 53-216 aa |
|
| ZNRF3-19221M | Recombinant Mouse ZNRF3 Protein | Mammalian Cell | Mouse | His |
|
|
| ZNRF3-10493M | Recombinant Mouse ZNRF3 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
|
| ZNRF3-10493M-B | Recombinant Mouse ZNRF3 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
||
| ZNRF3-1523H | Recombinant Human ZNRF3 protein, His-tagged | Yeast | Human | His | 56-219aa |
|
| ZNRF3-1524H | Recombinant Human ZNRF3 protein, His-tagged | Insect Cell | Human | His | 56-219aa |
|
| ZNRF3-1910H | Recombinant Human ZNRF3 Protein (56-219 aa), His-SUMO-tagged | E.coli | Human | His&SUMO | 56-219 aa |
|
| ZNRF3-2111H | Active Recombinant Human ZNRF3 protein, His-tagged | HEK293 | Human | His | Lys 56 - Met 219 |
|
| ZNRF3-4636H | Recombinant Human ZNRF3 protein | E.coli | Human | Non | 56-219aa |
|
Involved Pathway
ZNRF3 involved in several pathways and played different roles in them. We selected most pathways ZNRF3 participated on our site, such as Regulation of FZD by ubiquitination,Signal Transduction,Signaling by Wnt, which may be useful for your reference. Also, other proteins which involved in the same pathway with ZNRF3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Signaling by Wnt | KREMEN2,SOX9B,HECW1B,BCL9L,RYK,GPR177,PRICKLE1,SRY,C,WNT8-2 |
| Regulation of FZD by ubiquitination | RSPO4,LGR5,LGR4,FMNL3,LGR6,RNF43,RSPO2,RSPO3,RSPO1 |
| TCF dependent signaling in response to WNT | RNF43,KLHL12,RBBP5,LEO1,RSPO4,SOX9B,PYGO2,SOX9A,LGR6,SOX7 |
| Signal Transduction | TJP2B,RGS17,ARHGAP26,PRKCHB,PDK2,INSL5,ABR,NOXA1,CCBP2,RDH13 |
Protein Function
ZNRF3 has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity,coenzyme F420-0 gamma-glutamyl ligase activity,coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ZNRF3 itself. We selected most functions ZNRF3 had, and list some proteins which have the same functions with ZNRF3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ribosomal S6-glutamic acid ligase activity | ZNRF2B,RNF149,HERC2,MARCH6,UBR1,RNF187,MARCH9,RNF144AA,SIAH2L,TRIM71 |
| frizzled binding | WNT7B,WNT5A,DVL3A,WNT6,WNT10B,WNT3A,WNT2,WNT7AA,WNT16,DVL3 |
| metal ion binding | NOS2B,SMAD6,ZFP629,AEBP2,RACGAP1,ZFP90,MTHFS,IRF2BP1,CTH1,LFNG |
| protein-glycine ligase activity, initiating | RNF149,TTLL3,LTN1,MYLIPA,RNF144AB,G2E3,MARCH9,HECW2,MARCH6,RNF169 |
| protein-glutamic acid ligase activity | HECW2,UBE2IA,MYLIPB,UBR1,MARCH4,ITCHA,SHRPRBCK1R,MARCH11,HERC2,RNF144AA |
| coenzyme F420-2 alpha-glutamyl ligase activity | ARIH1L,NEURL1B,G2E3,MARCH9,ITCHA,RNF169,SIAH2L,RC3H2,SIAH1A,RNF149 |
| ligase activity | UBE3C,TRIM50,RNF185,SHRPRBCK1R,TRIM37,RBX1,MUL1A,UHRF1,NAPRT,RLIM |
| coenzyme F420-0 gamma-glutamyl ligase activity | HERC2,MARCH4,HECW2,RNF144AA,UBE2IA,MARCH5L,RNF169,TRIM41,RNF149,MARCH11 |
| tubulin-glycine ligase activity | MARCH4,LTN1,TRIM41,G2E3,FLR,MGRN1A,SIAH1A,RNF144AB,RNF187,TRIM50 |
Interacting Protein
ZNRF3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZNRF3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZNRF3.
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References
- Stinton, LM; Myers, RP; et al. Clinical associations and potential novel antigenic targets of autoantibodies directed against rods and rings in chronic hepatitis C infection. BMC GASTROENTEROLOGY 13:-(2013).
- Xu, ZY; Nie, P; et al. Molecular identification and expression analysis of tumor necrosis factor receptor-associated factor 2 in grass carp Ctenopharyngodon idella. ACTA BIOCHIMICA ET BIOPHYSICA SINICA 39:857-868(2007).
