UBXN11
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Official Full Name
UBX domain protein 11 -
Overview
This gene encodes a protein with a divergent C-terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C-terminal region. It also interacts with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation. It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity through upstream signaling pathways. The 3 coding sequence of this gene contains a polymoprhic region of 24 nt tandem repeats. Several transcripts containing between 1.5 and five repeat units have been reported. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
UBXN11;UBX domain protein 11;UBX domain containing 5 , UBXD5;UBX domain-containing protein 11;SOC;SOCI;socius;UBX domain-containing protein 5;colorectal tumor-associated antigen-1;colorectal tumor-associated antigen COA-1;COA-1;UBXD5;PP2243;D
Recombinant Proteins
- Human
- Mouse
- Rat
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| UBXN11-3566H | Recombinant Human UBXN11, GST-tagged | E.coli | Human | GST | 1-324aa | |
| UBXN11-2552H | Recombinant Human UBXN11 protein, His-tagged | E.coli | Human | His | 1-324 aa | |
| UBXN11-17771M | Recombinant Mouse UBXN11 Protein | Mammalian Cells | Mouse | His |
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| UBXN11-31555TH | Recombinant Human UBXN11, His-tagged | E.coli | Human | His | 191-400 a.a. |
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| UBXN11-6415R | Recombinant Rat UBXN11 Protein | Mammalian Cells | Rat | His |
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| UBXN11-476H | Recombinant Human UBXN11 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| UBXN11-5302H | Recombinant Human UBXN11 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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| UBXN11-6071R | Recombinant Rat UBXN11 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| UBXN11-6071R-B | Recombinant Rat UBXN11 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| UBXN11-9865M | Recombinant Mouse UBXN11 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| UBXN11-9865M-B | Recombinant Mouse UBXN11 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
UBXN11 involved in several pathways and played different roles in them. We selected most pathways UBXN11 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with UBXN11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
UBXN11 has several biochemical functions, for example, protein binding,ubiquitin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by UBXN11 itself. We selected most functions UBXN11 had, and list some proteins which have the same functions with UBXN11. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | ATP1B1,CTIF,POP1,GPC3,BMX,SCARA5,KLF10,ZNF581,OLA1,COX5B |
| ubiquitin binding | UBXN2B,SHRPRBCK1R,FAF1,OTUB2,SIRT2,C6orf106,VPS28,PER2,OTUB1B,TOP2A |
Interacting Protein
UBXN11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UBXN11 here. Most of them are supplied by our site. Hope this information will be useful for your research of UBXN11.
TRAF2;C6orf165;PRKAB2;EIF4E2;RHOBTB3;EIF4E
Resources
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References
- Chopra, VS; Srinivasan, A; et al. Transcriptional activation by GAGA factor is through its direct interaction with dmTAF3. DEVELOPMENTAL BIOLOGY 317:660-670(2008).
- Schuberth, C; Buchberger, A; et al. Membrane-bound Ubx2 recruits Cdc48 to ubiquitin ligases and their substrates to ensure efficient ER-associated protein degradation. NATURE CELL BIOLOGY 7:999-U102(2005).
- Ryoo, HD; Mann, RS; et al. The control of trunk Hox specificity and activity by Extradenticle. GENES & DEVELOPMENT 13:1704-1716(1999).
- Hagstrom, K; Muller, M; et al. A Polycomb and GAGA dependent silencer adjoins the Fab-7 boundary in the Drosophila bithorax complex. GENETICS 146:1365-1380(1997).
