SULT1E1
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Official Full Name
sulfotransferase family 1E, estrogen-preferring, member 1 -
Overview
isozyme that catalyzes the sulfation of estrogens, including beta-estradiol and estrone, but not of dehydroepiandrosterone, pregnenolone, cortisol or testosterone; plays a role in estrogen metabolism -
Synonyms
SULT1E1;sulfotransferase family 1E, estrogen-preferring, member 1;estrogen sulfotransferase;estrogen-preferring;EST;EST-1;EST1;estrone sulfotransferase;ST1E1;ST1E1_HUMAN;STE;Sulfotransferase 1E1;Sulfotransferase;Sulfotransferase estrogen preferring;EST-3;estrogen sulfotransferase, isoform 1;estrogen sulfotransferase, isoform 3;sulfotransferase family 1E, member 1;sulfotransferase, estrogen preferring;sulfotransferase, estr;ESTSUL
Recombinant Proteins
- Human
- Rat
- Cynomolgus
- E.coli
- Mammalian Cell
- HEK293
- Mouse
- Rabbit
- GST
- His
- Non
- His&Fc&Avi
Involved Pathway
SULT1E1 involved in several pathways and played different roles in them. We selected most pathways SULT1E1 participated on our site, such as Steroid hormone biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with SULT1E1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Steroid hormone biosynthesis | COMTA,CYP3A65,CYP2C55,CYP19A1A,CYP2B19,CYP7B1,UGT1A6A,CYP11C1,HSD3B2,UGT1A7C |
Protein Function
SULT1E1 has several biochemical functions, for example, estrone sulfotransferase activity,flavonol 3-sulfotransferase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SULT1E1 itself. We selected most functions SULT1E1 had, and list some proteins which have the same functions with SULT1E1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| steroid binding | GPR30,ESR2A,CYP21A1,FAM84B,ESRRGB,ESRRA,CYP21A2,HSD17B10,HSD3B4,ESRRB |
| estrone sulfotransferase activity | SULT1ST6,SULT1ST2 |
| flavonol 3-sulfotransferase activity | SULT1A1,SULT1A2 |
| protein binding | SYT16,OBFC1,ZNF346,OAZ2,TP53BP1,FLI1,PTPN9,CALM3,SLC5A1,CNOT6L |
| steroid sulfotransferase activity | SULT1A1,SULT2B1 |
Interacting Protein
SULT1E1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SULT1E1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SULT1E1.
PDE9A;SULT2B1;TP53;EEF1A1;UNC119;SETDB1;RBM48;RIF1;COPS6;ENOX1;IGSF21;C14orf1
Resources
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References
- Gong, JC; Gan, JP; et al. Identification of the Oxidative and Conjugative Enzymes Involved in the Biotransformation of Brivanib. DRUG METABOLISM AND DISPOSITION 40:219-226(2012).
- Riches, Z; Stanley, EL; et al. Quantitative Evaluation of the Expression and Activity of Five Major Sulfotransferases (SULTs) in Human Tissues: The SULT "Pie". DRUG METABOLISM AND DISPOSITION 37:2255-2261(2009).
