SULT1A3
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Official Full Name
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 -
Overview
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a phenol sulfotransferase with thermolabile enzyme activity. Four sulfotransferase genes are located on the p arm of chromosome 16; this gene and SULT1A4 arose from a segmental duplication. This gene is the most centromeric of the four sulfotransferase genes. Read-through transcription exists between this gene and the upstream SLX1A (SLX1 structure-specific endonuclease subunit homolog A) gene that encodes a protein containing GIY-YIG domains. -
Synonyms
SULT1A3;sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3;STM;sulfotransferase 1A3/1A4;TL PST;sulfokinase;phenol sulfotransferase 1A5;aryl sulfotransferase 1A3/1A4;dopamine-specific sulfotransferase;placental estrogen sulfotrans
Recombinant Proteins
- Human
- Rhesus macaque
- human
- E.coli
- Mammalian Cell
- HEK293
- HIS
- Non
- His
- His&SUMO
- GST
- His&Fc&Avi
Involved Pathway
SULT1A3 involved in several pathways and played different roles in them. We selected most pathways SULT1A3 participated on our site, such as Chemical carcinogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with SULT1A3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Chemical carcinogenesis | UGT1A7,CYP2C37,CYP2C54,SULT1A1,CYP2A6,GSTA2,AKR1C2,FAM84B,CYP2C50,CYP3A7 |
Protein Function
SULT1A3 has several biochemical functions, for example, aryl sulfotransferase activity,protein binding,sulfotransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SULT1A3 itself. We selected most functions SULT1A3 had, and list some proteins which have the same functions with SULT1A3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| aryl sulfotransferase activity | SULT1A4,SULT1A2,SULT1B1,SULT1D1,SULT1A1 |
| sulfotransferase activity | SULT2ST1,SULT1C2,SULT1A1,HS3ST3A1,SULT1ST8,HS3ST1,HS3ST3L,HS6ST3B,HS6ST1B,SULT3ST3 |
| protein binding | U2AF2,TNIP2,NR4A1,ZNF624,BRD3,AMY1A,NKX2,BTN2A2,GOLM1,MAPK8IP2 |
Interacting Protein
SULT1A3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SULT1A3 here. Most of them are supplied by our site. Hope this information will be useful for your research of SULT1A3.
SHMT1;KHDRBS2;NIF3L1;TK1;SMN1
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