SRPK2
-
Official Full Name
SRSF protein kinase 2 -
Synonyms
SRPK2;SRSF protein kinase 2;SFRS protein kinase 2;serine/arginine rich splicing factor kinase 2;SFRSK2;SR protein kinase 2;H_RG152G17.1a;H_RG152G17.1b;WUGSC:H_RG152G17.1a;serine kinase SRPK2;SR-protein-specific kinase 2;serine/threonine-protein
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- E.coli
- Mammalian Cell
- Sf9 Insect Cell
- HEK293
- E. coli
- Insect Cell
- HEK293T
- Mammalian cells
- Insect (sf21)
- His
- Non
- GST
- Myc&DDK
- His&Fc&Avi
Involved Pathway
SRPK2 involved in several pathways and played different roles in them. We selected most pathways SRPK2 participated on our site, such as mRNA processing, which may be useful for your reference. Also, other proteins which involved in the same pathway with SRPK2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| mRNA processing | RBM39A,SFRS3A,HNRNPH2,HNRPL,SF3A1,HNRNPL,PPM1G,RPL36A-HNRNPH2,CLK1,RBMS3 |
Protein Function
SRPK2 has several biochemical functions, for example, 14-3-3 protein binding,ATP binding,magnesium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SRPK2 itself. We selected most functions SRPK2 had, and list some proteins which have the same functions with SRPK2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 14-3-3 protein binding | IRS2,HDAC7A,ARRB2,AANAT,PRKCZ,RPTOR,TSC2,KIF13B,PRKCE,ZFP36 |
| protein serine/threonine kinase activity | CDC42BPG,CDK1,PASK,TNNI3K,PIK3R4,TGFBR1,DYRK1A,CAMK2G1,BMPR1A,NEK5 |
| ATP binding | EPHB3A,GLUD1,DMPK,CLK2A,FARSA,ACSS2,RPS6KA1,DHX32A,TYRO3,JAK3 |
| protein binding | SEMA4D,Ntng2,DCAF8,NLRC5,RPS6KC1,MIIP,HHLA2,DAXX,HSPG2,MSH5 |
| poly(A) RNA binding | MRPS7,C14orf21,TTC6,ZFP598,ANKRD17,ZNFX1,RBFOX2,EIF4A2,LBR,HNRNPM |
| magnesium ion binding | MARK1,COMT,ATP8B5,ADSS,LATS1,MAPK12,MAP3K5,PPM1B,FIGNL1,GTPBP10 |
Interacting Protein
SRPK2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SRPK2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SRPK2.
U2AF1;RBM39;PRPF38A
Resources
Related Services
Related Products
References
- Koizumi, J; Okamoto, Y; et al. The subcellular localization of SF2/ASF is regulated by direct interaction with SR protein kinases (SRPKs). JOURNAL OF BIOLOGICAL CHEMISTRY 274:11125-11131(1999).
