SLC39A13
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Official Full Name
solute carrier family 39 (zinc transporter), member 13 -
Overview
This gene encodes a member of the LIV-1 subfamily of the ZIP transporter family. The encoded transmembrane protein functions as a zinc transporter. Mutations in this gene have been associated with the spondylocheiro dysplastic form of Ehlers-Danlos syndrome. -
Synonyms
SLC39A13;solute carrier family 39 (zinc transporter), member 13;solute carrier family 39 (metal ion transporter), member 13;zinc transporter ZIP13;FLJ25785;LIV-1 subfamily of ZIP zinc transporter 9;LZT-Hs9;S39AD_HUMAN;Solute carrier family 39 member 13;ZIP-13;Zrt- and Irt-like protein 13
Recombinant Proteins
- Human
- Zebrafish
- Chicken
- Rhesus macaque
- Rat
- zebrafish
- E.coli
- Mammalian Cell
- HEK293
- E.coli expression system
- His
- Non
- His&GST
- His&Fc&Avi
Involved Pathway
SLC39A13 involved in several pathways and played different roles in them. We selected most pathways SLC39A13 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC39A13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
SLC39A13 has several biochemical functions, for example, protein binding,protein homodimerization activity,zinc ion transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC39A13 itself. We selected most functions SLC39A13 had, and list some proteins which have the same functions with SLC39A13. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | TNFAIP3,NR2F1,TATDN1,NME7,UHRF1,SRSF5,ITPR3,NSMAF,SPSB4,TRIM26 |
| protein homodimerization activity | COMMD1,HNF1B,ROPN1B,S100A16,GAMT,MYH9,AMICA1,SEPT12,SRR,HMGCS1 |
| zinc ion transmembrane transporter activity | SLC39A3,SLC30A10,SLC11A2,SLC30A6,SLC39A6,SLC39A10,SLC30A8,SLC30A1A,SLC30A2,SLC39A11 |
Interacting Protein
SLC39A13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC39A13 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC39A13.
TCF4;REL;MAPK8IP2
Resources
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References
- Brommage, R; Liu, J; et al. High-throughput screening of mouse gene knockouts identifies established and novel skeletal phenotypes. BONE RESEARCH 2:-(2014).
- Xiao, GR; Wan, ZH; et al. The metal transporter ZIP13 supplies iron into the secretory pathway in Drosophila melanogaster. ELIFE 3:-(2014).
