RELB
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Official Full Name
RELB v-rel reticuloendotheliosis viral oncogene homolog B -
Synonyms
RELB;v-rel reticuloendotheliosis viral oncogene homolog B;v rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide gene enhancer in B cells 3);transcription factor RelB;REL B;v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3;v-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3);IREL;I-REL;REL-B
Recombinant Proteins
- Human
- Mouse
- Chicken
- E.coli
- Sf9 Cells
- E.coli
- Mammalian Cells
- HEK293
- His
- T7
- Non
- Flag
- Avi
- Fc
- Myc
- DDK
Involved Pathway
RELB involved in several pathways and played different roles in them. We selected most pathways RELB participated on our site, such as MAPK signaling pathway,NF-kappa B signaling pathway,Osteoclast differentiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with RELB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| MAPK signaling pathway | GADD45B,ELK4,MAPK12B,CACNA1BA,RPS6KA3B,FGF13A,PPM1BA,PPP3R1,MAP4K4,MAX |
| Osteoclast differentiation | RELA,MAPK11,MAPK12,SIRPG,IL1B,NFKBIA,FOS,AKT1,PIK3R3,TGFB2 |
| NF-kappa B signaling pathway | CXCL2,CXCL12,LTBR,Ccl21c,TLR4,LBP,CCL21B,PLCG2,LTA,DDX58 |
| Epstein-Barr virus infection | CSNK2A2,HLA-C,TAB2,POLR3D,MAPK12,POLR2A,MDM2,SFPI1,MAP2K7,HDAC2 |
| HTLV-I infection | Fzd4,RB1,TSPO,TGFB2,FZD5,POLB,SLC25A31,TBPL1,POLE,HLA-DQB1 |
Protein Function
RELB has several biochemical functions, for example, RNA polymerase II regulatory region sequence-specific DNA binding,RNA polymerase II transcription factor activity, sequence-specific DNA binding,chromatin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RELB itself. We selected most functions RELB had, and list some proteins which have the same functions with RELB. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription factor activity, sequence-specific DNA binding | RUNX3,SIM2,GLI2,PKNOX1,PPARDB,HOXA3A,ZFP322A,MYNN,ZIK1,DMRT2A |
| RNA polymerase II transcription factor activity, sequence-specific DNA binding | NFIB,BETA3,LMO2,FOXG1B,BMPR1A,FOXG1D,MITFA,SPI1B,SP4,HIF3A |
| protein binding | CITED1,LYSMD1,TADA3,NUAK1,RADIL,TEKT4,TAF8,PTGIS,KRTAP12-2,SLAMF1 |
| chromatin binding | SUV39H1,POLE,CHAF1B,ANKRD17,DNMT1,PHC1,SAFB,CDCA5,KDM6B,POLR2B |
| RNA polymerase II regulatory region sequence-specific DNA binding | IKZF3,SOHLH1,HOXD8,BARX1,CREB3,CSDA,JARID2,MEF2D,KAT2B,E4F1 |
| core promoter binding | GATA1,INSM1B,HDAC2,SFPQ,HDAC6,TFAP2C,KDM3A,CRY1,MYBBP1A,IFI16 |
| transcription corepressor activity | SIRT1,PEX14,PBXIP1,E2F8,ZEB1,SETD8,TBL1X,CIR1,POU1F1,TSG101 |
Interacting Protein
RELB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RELB here. Most of them are supplied by our site. Hope this information will be useful for your research of RELB.
NFKB1;NFKB2;RELA;GSK3B;COMMD1;NFKB2;NFKBIE
Resources
Research Area
Apoptosis Transcription Factors and RegulatorsNFkB
IL-17 Signaling Related Molecules
Dendritic Cell Development
Related Services
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References
- Thomas, R; et al. Dendritic cells as targets or therapeutics in rheumatic autoimmune disease. CURRENT OPINION IN RHEUMATOLOGY 26:211-218(2014).
- Dohi, T; Kawashima, R; et al. Pathological activation of canonical nuclear-factor kappa B by synergy of tumor necrosis factor alpha and TNF-like weak inducer of apoptosis in mouse acute colitis. CYTOKINE 69:14-21(2014).
