PTPRM

  • Official Full Name

    protein tyrosine phosphatase, receptor type, M
  • Overview

    The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic tra
  • Synonyms

    PTPRM;protein tyrosine phosphatase, receptor type, M;PTPRL1;receptor-type tyrosine-protein phosphatase mu;hR PTPu;RPTPU;protein tyrosine phosphatase mu;protein-tyrosine phosphatase mu;protein tyrosine phosphatase, receptor type, mu polypeptide;RP

Recombinant Proteins

  • Human
  • Mouse
  • E.coli
  • Mammalian Cell
  • Sf9 Insect Cell
  • HEK293
  • Non
  • His
  • GST
  • His&T7
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
PTPRM-336H Active Recombinant Human Protein Tyrosine Phosphatase, Receptor Type, M E.coli Human Non
PTPRM-13701M Recombinant Mouse PTPRM Protein Mammalian Cell Mouse His
PTPRM-1861H Recombinant Human PTPRM, GST-tagged E.coli Human GST
PTPRM-2384H Recombinant Human PTPRM, GST-tagged E.coli Human GST 839-1100 a.a.
PTPRM-382H Recombinant Human PTPRM, GST-tagged Sf9 Insect Cell Human GST 764-1452 a.a.
PTPRM-5469H Recombinant Human Protein Tyrosine Phosphatase, Receptor Type, M E.coli Human Non 839-1100 a.a.
PTPRM-5628H Recombinant Human PTPRM protein, His & T7-tagged E.coli Human His&T7 Thr1197~Ser1403
PTPRM-7017H Recombinant Human PTPRM , GST-tagged Sf9 Insect Cell Human GST 764-1452 aa
PTPRM-6108H Recombinant Human PTPRM Protein (Thr1197-Ser1403), N-His tagged E.coli Human His Thr1197-Ser1403
PTPRM-7288M Recombinant Mouse PTPRM Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
PTPRM-7288M-B Recombinant Mouse PTPRM Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    PTPRM involved in several pathways and played different roles in them. We selected most pathways PTPRM participated on our site, such as Cell adhesion molecules (CAMs),Adherens junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with PTPRM were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adherens junction TCF7L2,VCLA,AASS,SRC,WASLA,CDH1,PTPRFB,SMAD4,RHOAD,PTPRJ
    Cell adhesion molecules (CAMs) ITGAV,NLGN2B,PVRL1B,CLDN7A,CLDN14,ICAM3,SELL,NLGN3A,NEO1A,ITGB2L

    Protein Function

    PTPRM has several biochemical functions, for example, cadherin binding,identical protein binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PTPRM itself. We selected most functions PTPRM had, and list some proteins which have the same functions with PTPRM. You can find most of the proteins on our site.

    Function Related Protein
    cadherin binding CTNNA1,CTNNAL1,CTNNA3,PSEN1,JUP,CTNNB1,CDH13,CD46,NUMB,VCL
    identical protein binding PNMA5,CLDN8,FZD1,ABCD1,BNIP2,TRP63,AXIN1,CSNK2B,S100A4,MAP3K13
    protein binding EPHA7,C1orf182,KCNH7,POLD2,ZKSCAN5,ARPM1,U2AF1,TOB1A,MINOS1,ENG
    protein tyrosine phosphatase activity DUPD1,PTPN1,PTP4A1,PTPREB,CDC25A,MTMR7,MTM1,MTMR2,DUSP3B,CDC25C
    transmembrane receptor protein tyrosine phosphatase activity PTPRN2,PTPRA,EVLA,PTPN6,PTPRF,PTPRS,PTPRD,PTPRUB,PTPRO,PTPRE

    Interacting Protein

    PTPRM has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PTPRM here. Most of them are supplied by our site. Hope this information will be useful for your research of PTPRM.

    LCK;Cdh1;Cdh2;Cdh4;nagA

    Resources

    References

    • Luckerath, K; Kirkin, V; et al. Immune modulation by Fas ligand reverse signaling: lymphocyte proliferation is attenuated by the intracellular Fas ligand domain. BLOOD 117:519-529(2011).
    • Charba, DS; Wiggins, RC; et al. Antibodies to protein tyrosine phosphatase receptor type O (PTPro) increase glomerular albumin permeability (P(alb)). AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 297:F138-F144(2009).

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