PSMB7
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Official Full Name
proteasome (prosome, macropain) subunit, beta type, 7 -
Overview
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. The encoded protein is a member of the proteasome B-type family, also known as the T1B family, and is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon, and proteolytic processing is required to generate a mature subunit. A pseudogene of this gene is located on the long arm of chromosome 14. [provided by RefSeq, Jul 2012] -
Synonyms
PSMB7;proteasome (prosome, macropain) subunit, beta type, 7;Z;proteasome subunit beta type-7;macropain chain Z;proteasome subunit Z;proteasome subunit alpha;proteasome catalytic subunit 2;multicatalytic endopeptidase complex chain Z
Recombinant Proteins
- Human
- Rhesus macaque
- Zebrafish
- Rat
- Chicken
- E.coli
- Mammalian Cells
- HEK293
- T7
- His
- Non
- His&Fc&Avi
- GST
Involved Pathway
PSMB7 involved in several pathways and played different roles in them. We selected most pathways PSMB7 participated on our site, such as Proteasome, which may be useful for your reference. Also, other proteins which involved in the same pathway with PSMB7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Proteasome | PSMB2,PSME2,PSMC2,PSMB10,PSMC6,PSMD11B,POMP,IFNG,PSMD1,PSMA2 |
Protein Function
PSMB7 has several biochemical functions, for example, endopeptidase activity,protein binding,threonine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PSMB7 itself. We selected most functions PSMB7 had, and list some proteins which have the same functions with PSMB7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | AXIN2,CDKN1A,EFS,STK25,NSFL1C,ZNF232,TMED10,CRB3,KAT2A,KCTD13 |
| endopeptidase activity | PSEN2,F9,MMP1,KLK1B1,PSMB9,HTRA4,PSMA8,PSMB8F,KLK1B22,PSMB9A |
| threonine-type endopeptidase activity | PSMB2,PSMB3,PSMB10,PRSS50,PSMB4,PSMB5,PSMA1,PSMA6A,PSMA8,PSMA3 |
Interacting Protein
PSMB7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PSMB7 here. Most of them are supplied by our site. Hope this information will be useful for your research of PSMB7.
PSMB1;PSMB5;PSMB9
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