PRMT2
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Official Full Name
protein arginine methyltransferase 2 -
Overview
Protein arginine N-methyltransferase 2 is an enzyme that in humans is encoded by the PRMT2 gene. -
Synonyms
PRMT2;protein arginine methyltransferase 2;HMT1 (hnRNP methyltransferase, S. cerevisiae) like 1 , HMT1 hnRNP methyltransferase like 1 (S. cerevisiae) , HRMT1L1;protein arginine N-methyltransferase 2;MGC111373;PRMT2 beta;PRMT2 alpha;PRMT2 gamma;HM
Recombinant Proteins
- Human
- Rhesus macaque
- Zebrafish
- Mouse
- E.coli
- Wheat Germ
- Insect Cell
- Mammalian Cell
- HEK293
- HEK293T
- In Vitro Cell Free System
- His
- GST
- Non
- Flag
- Myc&DDK
- His&Fc&Avi
Involved Pathway
PRMT2 involved in several pathways and played different roles in them. We selected most pathways PRMT2 participated on our site, such as RB in Cancer,mRNA processing, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRMT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| mRNA processing | SFPQ,FAM120B,SF3B2,DDX20,RBM39,HNRNPA2B1,CELF2,ZFP740,RBM4B,RBM12B2 |
| RB in Cancer | SMARCA2,DCK,RABIF,TOP2A,RBP1,HMGB2,FAF1,ANLN,HLTF |
Protein Function
PRMT2 has several biochemical functions, for example, androgen receptor binding,estrogen receptor binding,histone methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PRMT2 itself. We selected most functions PRMT2 had, and list some proteins which have the same functions with PRMT2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription coactivator activity | DDX17,NPAT,TDRD3,RFXAP,BCL10,TFDP1B,CALCOCO1,YY1,VGLL1,MAK |
| histone-arginine N-methyltransferase activity | PRMT5,PRMT6,PRMT3,PRMT7,PRMT8,CARM1 |
| progesterone receptor binding | NCOA1 |
| signal transducer activity | TRAF5,TAS2R125,NPY8BR,OLFR11,GNA15.4,OPN1MW4,MUL1A,LPAR2B,TRAF2,OLFR24 |
| retinoic acid receptor binding | HMGA1,ASXL1,MED1,CTBP2,LRIF1,PRAMEF2,PRAMEF6,ACTN4,NSD1,PRAME |
| protein-arginine omega-N asymmetric methyltransferase activity | PRMT6,PRMT3,CARM1,PRMT8B,PRMT1,PRMT8,PRMT7 |
| androgen receptor binding | FHL2,Ar,FOXH1,TCF21,DDX5,RB1,KDM1A,CTNNB1,PIAS1,KDM3A |
| thyroid hormone receptor binding | MED4,MED24,MED17,NR0B2,TAF7,GTF2B,MED12,OASL,NCOA3,FUS |
| peroxisome proliferator activated receptor binding | PPARGC1A,HMGA1,ASXL2,CREBBP,HMGA1-RS1,NFATC4,ASXL1,MED1,IKBKG,NR0B2 |
Interacting Protein
PRMT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRMT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PRMT2.
ESR1;RB1;AKR1B1;PGR;NPM1;THRB;RXRA;HNRNPK
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