PPP1CC
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Official Full Name
protein phosphatase 1, catalytic subunit, gamma isozyme -
Overview
Protein phosphatase 1, gamma 1 (PP-1G) is a member of the PPP phosphatase family. Type 1 protein Ser/Thr phosphatases (PP1) have a high specific activity against phosphorylase, and are resistant to okadaic acid up to concentrations of 50 nM, but sensitive to Inhibitor-2 and microcystin LR. -
Synonyms
PPP1CC;protein phosphatase 1, catalytic subunit, gamma isozyme;protein phosphatase 1, catalytic subunit, gamma isoform;serine/threonine-protein phosphatase PP1-gamma catalytic subunit;PP1gamma;serine/threonine phosphatase 1 gamma;protein phosphatase 1C catalytic subunit;PP-1G;PPP1G
Recombinant Proteins
- Human
- Mouse
- Chicken
- Rhesus macaque
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- Myc&DDK
- His&Myc
- His&Fc&Avi
Involved Pathway
PPP1CC involved in several pathways and played different roles in them. We selected most pathways PPP1CC participated on our site, such as mRNA surveillance pathway,cGMP-PKG signaling pathway,cAMP signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP1CC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Regulation of Actin Cytoskeleton | FGF17,MYL2,MAP2K2,CHRM2A,ARHGEF4,FGF22,ITGB1B.2,MAP2K2B,FGD,ITGB3B |
| Adrenergic signaling in cardiomyocytes | ATP1B2A,ATP2B1A,CREB3L1,PRKACAA,CALM2,GNA11A,PPP1CAA,CALM4,CALML5,GNAI2B |
| Dopaminergic synapse | GNAI3,GNG7,ARRB2,PPP2R2C,ARNTL,TH,GNB1,DRD3,DRD5,PPP3CC |
| Oxytocin signaling pathway | NPR2,PLA2G4A,GUCY1A3,ITPR1,PRKAG3,NFATC4,CACNG4,MEF2C,PRKAA1,CAMK1D |
| Focal adhesion | RAF1B,RHOAC,ITGA5,PRKCBA,GRB2,COL4A6,Itga10&Itgb1,ITGA6B,CAPN2,MYLK2 |
| Alcoholism | GNGT1,CREB3L4,CREB5,HIST1H2BG,GM14478,GNG11,SHC3,H2AFV,GM14476,PRKACA |
| Herpes simplex infection | THOC4,MYD88,PER3,JAK2A,MHC2DEB,HLA-A,HNRPKL,PKZ,OAS2,ARNTL1B |
| Insulin resistance | NR1H3,PPP1CAA,MAPK8A,IRS2,MAPK8B,SLC2A2,PRKAG1,PPP1CB,SLC27A5,MAPK9 |
| Inflammatory mediator regulation of TRP channels | CYP2C38,P2RY2,KLK1B4,CYP2C39,CYP2J2,CYP2C55,MAPK10,PIK3CB,ACCN3,IL1R1 |
Protein Function
PPP1CC has several biochemical functions, for example, metal ion binding,phosphatase activity,phosphoprotein phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP1CC itself. We selected most functions PPP1CC had, and list some proteins which have the same functions with PPP1CC. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | RBM42,UTP15,GDI2,CROP,PCBP3,DIAP1,CDC42EP4,MRPL42,HSPA9,DNTTIP2 |
| protein binding | APOBEC2A,RARA,KRTAP9-4,IRF7,DYRK2,AMELX,RPRD1B,APOA1BP,ARNTL1A,MEGF6 |
| metal ion binding | ZNF668,ERI1,ASXL1,RNF11B,ZNF404,CYP2X8,SMAD2,CYP2C70,CYP46A1.3,ZNF785 |
| protein kinase binding | CDK5R1,ERRFI1,ACVRL1,CDC42,MAP2K6,CD8A,MAP3K1,RAB11FIP2,AP2A1,HDAC4 |
| protein serine/threonine phosphatase activity | PPM1AB,PDP2,PPP5C,PPM1NB,DUSP23,MTMR3,CTDNEP1,PPM1E,PPM1A,PPA2 |
| phosphoprotein phosphatase activity | PTEN,PTPN2A,PTPRFB,SSH2,PPM1BA,CPPED1,PDXP,PTPN4B,PPP4CB,CDC14AA |
| phosphatase activity | CDC14A,MTMR7A,PTPRQ,PTP4A2A,DUSP19B,EPHX2,C12orf5,MTMR1A,PGAM5,DUSP23B |
| protein N-terminus binding | NBN,EIF5A,GTF2H3,TRAF6,ZWINT,TGFB1,TSC1,KCNB1,STX5,NCOA1 |
Interacting Protein
PPP1CC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP1CC here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP1CC.
TP53BP2;PPP1R2;ZFYVE9;URI1
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