POLL
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Official Full Name
polymerase (DNA directed), lambda -
Overview
This gene encodes a DNA polymerase. DNA polymerases catalyze DNA-template-directed extension of the 3-end of a DNA strand. This particular polymerase, which is a member of the X family of DNA polymerases, likely plays a role in non-homologous end joining and other DNA repair processes. Alternatively spliced transcript variants have been described. -
Synonyms
POLL;polymerase (DNA directed), lambda;DNA polymerase lambda;BETA N;BETAN;DNA directed DNA polymerase lambda;DNA polymerase beta 2;DNA polymerase beta-2;DNA polymerase kappa;DNA polymerase kappa DNA polymerase beta N;DNA polymerase lamda2;DPOLL_HUMAN;EC 2.7.7.7,EC 4.2.99.;FLJ46002;OTTHUMP00000020321;OTTHUMP00000020323;OTTHUMP00000059179;Pol beta2;POL KAPPA;Pol Lambda;POLKAPPA;Polymerase DNA directed lambda;DNA polymerase beta-N
Recombinant Proteins
- Zebrafish
- Mouse
- Human
- Rhesus macaque
- Rat
- Cynomolgus
- Mammalian Cell
- E.coli
- HEK293
- Wheat Germ
- HEK293T
- In Vitro Cell Free System
- His
- Non
- Myc&DDK
- GST
- His&Fc&Avi
Involved Pathway
POLL involved in several pathways and played different roles in them. We selected most pathways POLL participated on our site, such as Base excision repair,Non-homologous end-joining, which may be useful for your reference. Also, other proteins which involved in the same pathway with POLL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Non-homologous end-joining | XRCC4,FEN1,MRE11A,PRKDC,POLM,XRCC6,XRCC5,LIG4,DCLRE1C,DNTT |
| Base excision repair | APEX1,HMGB1,mutY,NEIL3,NTHL1,UNG,APEX2,POLE3,LIG3,LIG1 |
Protein Function
POLL has several biochemical functions, for example, DNA binding,DNA-directed DNA polymerase activity,lyase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by POLL itself. We selected most functions POLL had, and list some proteins which have the same functions with POLL. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | CYP27C1,ZNF620,SGSH,ADSSL,MUS81,BIRC5,GYG1,KLF12,PVALB4,ZBTB1 |
| protein binding | PINX1,COQ7,ICAM5,KIF9,MLANA,SCAND1,CALML3,MSH2,CCDC123,SEC61G |
| DNA-directed DNA polymerase activity | POLB,PRIMPOL,POLI,POLE4,POLD1,POLA2,POLN,CCDC111,POLD4,POLM |
| DNA binding | TMPO,POLN,SOX6,POLR2K,RNF6,HNRNPU,THAP4,YBX2,PML,ZNF577 |
| lyase activity | AGXT2L2,ACLYA,ADCY1B,ETNPPL,ADCY1A,GC2,TYW1B,CRY5,TYW1,CBSA |
Interacting Protein
POLL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POLL here. Most of them are supplied by our site. Hope this information will be useful for your research of POLL.
UBC;XRCC1;LDOC1
Resources
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References
- Gerstenfeld, M; et al. The Run-Up to Israel's 2013 Elections: A Political History. ISRAEL AFFAIRS 21:177-194(2015).
- Salmanzadeh, M; Saeedi, M; et al. Characterization and metals fractionation of street dust samples from Tehran, Iran. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH 9:213-224(2015).
