PBK
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Official Full Name
PDZ binding kinase -
Overview
This genes encodes a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. This mitotic kinase may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. -
Synonyms
PBK;PDZ binding kinase;lymphokine-activated killer T-cell-originated protein kinase;cancer/testis antigen 84;CT84;FLJ14385;Nori 3;SPK;T LAK cell originated protein kinase;TOPK;PDZ-binding kinase;MAPKK-like protein kinase;serine/threonine prote
Recombinant Proteins
- Human
- Mouse
- Chicken
- Zebrafish
- Insect Cells
- Mammalian Cell
- E.coli
- Insect Cell
- Sf9 Insect Cell
- HEK293
- HEK293T
- Mammalian cells
- Insect (sf21)
- His
- His&T7
- Non
- GST
- His&Fc&Avi
- Myc&DDK
- Flag
Involved Pathway
PBK involved in several pathways and played different roles in them. We selected most pathways PBK participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PBK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
PBK has several biochemical functions, for example, ATP binding,protein binding,protein serine/threonine kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PBK itself. We selected most functions PBK had, and list some proteins which have the same functions with PBK. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | CAMK2D,PRKCDA,ABCF2A,EHD1,ABCB6A,FICD,UBE2O,H1FNT,BBS12,TTBK2 |
| protein serine/threonine kinase activity | AKT2,GSK3B,MAP3K10,STK17B,TRPM6,PIM1,LATS1,CAMKK1A,PHKG2,MAP2K5 |
| protein binding | ATRIP,ABCF3,CD99L2,CINP,PHF16,FSTL5,KCNQ1,YTHDC1,ZNHIT3,DUT |
Interacting Protein
PBK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PBK here. Most of them are supplied by our site. Hope this information will be useful for your research of PBK.
TP53;DLG1;MBP;CDK1;CSNK2A2;TRIM37;RAF1
Resources
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References
- O'Leary, PC; Penny, SA; et al. Systematic antibody generation and validation via tissue microarray technology leading to identification of a novel protein prognostic panel in breast cancer. BMC CANCER 13:-(2013).
- Arce-Fonseca, M; Ballinas-Verdugo, MA; et al. Specific humoral and cellular immunity induced by Trypanosoma cruzi DNA immunization in a canine model. VETERINARY RESEARCH 44:-(2013).
