NRTN
-
Official Full Name
neurturin -
Overview
Neurturin is a member of the TGF-beta subfamily, TRN. This gene signals through RET and a GPI-linked coreceptor, and promotes survival of neuronal populations. A neurturin mutation has been described in a family with Hirschsprung Disease. [provided by RefSeq, Jul 2008] -
Synonyms
NRTN;neurturin;NTN;prepro-neurturin
Recombinant Proteins
- Human
- Mouse
- Chicken
- E.coli
- Mammalian Cell
- HEK293
- Non
- His
- His&Fc&Avi
Involved Pathway
NRTN involved in several pathways and played different roles in them. We selected most pathways NRTN participated on our site, such as Axon guidance,Developmental Biology,NCAM signaling for neurite out-growth, which may be useful for your reference. Also, other proteins which involved in the same pathway with NRTN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Developmental Biology | EPHA2A,RNF8,EGR2,KALRN,RASGRP1,INSM1B,PRDM14,PCSK6,CD24,SREBF2 |
| NCAM1 interactions | PSPN,GFRA1,COL9A1A,GFRA4,COL9A1B,GFRA2,GDNF |
| Axon guidance | RND1,PAK4,ACTR3,GPC1B,GFRA1,PAK3,PITPNA,EPHB4B,ITGB1,COL9A1 |
| NCAM signaling for neurite out-growth | GFRA1,GFRA2,ST8SIA2,GDNF,COL9A1A,PSPN,GFRA4,COL9A1B |
Protein Function
NRTN has several biochemical functions, for example, growth factor activity,receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NRTN itself. We selected most functions NRTN had, and list some proteins which have the same functions with NRTN. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| receptor binding | RIPK2,PVRL3B,TRIM24,HAO2,CD86,STOML2,IAPP,LGI1,ACOX1,PSPN |
| growth factor activity | LIF,TDGF1,BMP3,FGF11A,BDNF,FGF1B,BMP7A,FGF16,GPR19,MDK |
Interacting Protein
NRTN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NRTN here. Most of them are supplied by our site. Hope this information will be useful for your research of NRTN.
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