MC1R
-
Official Full Name
melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) -
Overview
This intronless gene encodes the receptor protein for melanocyte-stimulating hormone (MSH). The encoded protein, a seven pass transmembrane G protein coupled receptor, controls melanogenesis. Two types of melanin exist: red pheomelanin and black eumelanin. Gene mutations that lead to a loss in function are associated with increased pheomelanin production, which leads to lighter skin and hair color. Eumelanin is photoprotective but pheomelanin may contribute to UV-induced skin damage by generating free radicals upon UV radiation. Binding of MSH to its receptor activates the receptor and stimulates eumelanin synthesis. This receptor is a major determining factor in sun sensitivity and is a genetic risk factor for melanoma and non-melanoma skin cancer. Over 30 variant alleles have been identified which correlate with skin and hair color, providing evidence that this gene is an important component in determining normal human pigment variation. -
Synonyms
MC1R;melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor);melanocyte-stimulating hormone receptor;MSH R;MC1-R;Melanocortin 1 receptor;Melanocortin receptor 1;MSH-R;MSHR;MSHR_HUMAN;melanotropin receptor;CMM5;SHEP2
Recombinant Proteins
- Human
- Chicken
- Zebrafish
- Mouse
- Vulpes vulpes (Red fox)
- Leontopithecus rosalia (Golden lion tamarin)
- Mandrillus sphinx (Mandrill) (Papio sphinx)
- Trachypithecus auratus (Javan langur)
- Eulemur fulvus fulvus (Brown lemur)
- Felis catus
- Macaca sylvanus (Barbary macaque)
- Cercopithecus neglectus (De Brazza's monkey)
- Cervus elaphus
- Panthera onca (Jaguar) (Felis onca)
- Macaca mulatta
- Saguinus fuscicollis (Brown-headed tamarin)
- Puma yagouaroundi (Jaguarundi) (Herpailurus yagouaroundi)
- Sheep
- Pongo Pygmaeus
- Cercopithecus mitis (Blue monkey)
- Leontopithecus chrysomelas (Golden-headed lion tamarin)
- Sus scrofa (Pig)
- Horse
- Trachypithecus francoisi (Francois' leaf monkey) (Presbytis francoisi)
- Capreolus capreolus (Roe deer)
- Hapalemur griseus (Gray gentle lemur) (Eastern lesser bamboo lemur)
- Callithrix geoffroyi (Geoffroy's marmoset)
- Pan troglodytes
- Erythrocebus patas (Red guenon) (Cercopithecus patas)
- Semnopithecus entellus (Hanuman langur) (Presbytis entellus)
- Miopithecus talapoin (Angolan talapoin) (Cercopithecus talapoin)
- Chaetodipus baileyi (Bailey's pocket mouse) (Perognathus baileyi)
- Alouatta pigra (Guatemalan howler monkey) (Mexican black howler monkey)
- Alouatta seniculus (Red howler monkey)
- Trachypithecus cristatus (Silvered leaf-monkey) (Presbytis cristata)
- Callimico goeldii (Goeldi's marmoset)
- Allenopithecus nigroviridis (Allen's swamp monkey)
- Mammuthus primigenius (Siberian woolly mammoth)
- Colobus guereza (Mantled guereza) (Eastern black-and-white colobus monkey)
- Presbytis comata (Grizzled leaf monkey)
- Saguinus imperator (Emperor tamarin)
- Dog
- Loris tardigradus (Slender loris)
- Goat
- Rangifer tarandus (Reindeer) (Cervus tarandus)
- Saguinus oedipus (Cotton-top tamarin)
- Leontopithecus chrysopygus (Golden-rumped lion tamarin) (Leontopithecus rosalia chrysopygus)
- Dama dama (Fallow deer) (Cervus dama)
- Varecia variegata rubra (Red ruffed lemur) (Varecia rubra)
- Varecia variegata variegata (Black and white ruffed lemur)
- Lemur catta (Ring-tailed lemur)
- Alces alces alces (European moose) (Elk)
- Vulpes lagopus (Arctic fox) (Alopex lagopus)
- Callithrix pygmaea (Pygmy marmoset) (Cebuella pygmaea)
- Callithrix jacchus (White-tufted-ear marmoset)
- Ovibos moschatus (Muskox)
- Hylobates lar (Common gibbon) (White-handed gibbon)
- Galago senegalensis (Northern lesser bushbaby) (Senegal bushbaby)
- Ateles paniscus (Black spider monkey) (Red-faced black spider monkey)
- Bovine
- Papio hamadryas (Hamadryas baboon)
- Callithrix argentata (Silvery marmoset) (Mico argentatus)
- Cebus albifrons (White-fronted capuchin)
- Nomascus concolor (Black crested gibbon) (Hylobates concolor)
- Chaetodipus penicillatus (Desert pocket mouse) (Perognathus penicillatus)
- Alouatta palliata (Mantled howler monkey)
- Saguinus midas (Midas tamarin) (Golden-handed tamarin)
- Saimiri oerstedii (Central American squirrel monkey)
- Chlorocebus Aethiops
- Cercopithecus diana (Diana monkey)
- Trachypithecus obscurus (Dusky leaf-monkey) (Presbytis obscura)
- Alouatta sara (Bolivian red howler monkey)
- Macaca silenus (Lion-tailed macaque)
- Gorilla gorilla gorilla (Western lowland gorilla)
- Mus musculus
- Alouatta caraya (Black howler monkey)
- Papio anubis (Olive baboon)
- Macaca nigra (Celebes black macaque) (Crested black macaque)
- Hylobates muelleri (Mueller's Bornean gibbon)
- Saguinus geoffroyi (Geoffroy's tamarin)
- Macaca nemestrina (Pig-tailed macaque)
- Wheat Germ
- Mammalian Cell
- HEK293
- Wheat Germ (in vitro)
- E.coli expression system
- Non
- His
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MC1R-29451TH | Recombinant Human MC1R | Wheat Germ | Human | Non | 100 amino acids |
|
| MC1R-3109C | Recombinant Chicken MC1R | Mammalian Cell | Chicken | His |
|
|
| MC1R-9612Z | Recombinant Zebrafish MC1R | Mammalian Cell | Zebrafish | His |
|
|
| MC1R-4434HCL | Recombinant Human MC1R 293 Cell Lysate | HEK293 | Human | Non |
|
|
| Mc1r-0183M | Recombinant Mouse Mc1r Full Length Transmembrane Protein(1-315aa), His-tagged(VLPs) | HEK293 | Mouse | His | Full L. 1-315aa |
|
| MC1R-3087HFL | Recombinant Human MC1R Protein, Full Length, N-GST tagged | Wheat Germ (in vitro) | Human | GST | Full L. Full Length |
|
| RFL10108VF | Recombinant Full Length Vulpes Vulpes Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Vulpes vulpes (Red fox) | His | Full L. Full Length (1-317) |
|
| RFL10130LF | Recombinant Full Length Leontopithecus Rosalia Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Leontopithecus rosalia (Golden lion tamarin) | His | Full L. Full Length (1-318) |
|
| RFL10558MF | Recombinant Full Length Mandrillus Sphinx Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Mandrillus sphinx (Mandrill) (Papio sphinx) | His | Full L. Full Length (1-317) |
|
| RFL10997TF | Recombinant Full Length Trachypithecus Auratus Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Trachypithecus auratus (Javan langur) | His | Full L. Full Length (1-317) |
|
| RFL1229EF | Recombinant Full Length Eulemur Fulvus Fulvus Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Eulemur fulvus fulvus (Brown lemur) | His | Full L. Full Length (1-317) |
|
| RFL14300FF | Recombinant Full Length Cat Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Felis catus | His | Full L. Full Length (1-317) |
|
| RFL14475MF | Recombinant Full Length Macaca Sylvanus Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Macaca sylvanus (Barbary macaque) | His | Full L. Full Length (1-317) |
|
| RFL15019CF | Recombinant Full Length Cercopithecus Neglectus Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Cercopithecus neglectus (De Brazza's monkey) | His | Full L. Full Length (1-317) |
|
| RFL15327CF | Recombinant Full Length Cervus Elaphus Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Cervus elaphus | His | Full L. Full Length (1-317) |
|
| RFL15670PF | Recombinant Full Length Panthera Onca Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Panthera onca (Jaguar) (Felis onca) | His | Full L. Full Length (1-317) |
|
| RFL15814MF | Recombinant Full Length Macaca Mulatta Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Macaca mulatta | His | Full L. Full Length (1-317) |
|
| RFL16270SF | Recombinant Full Length Saguinus Fuscicollis Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Saguinus fuscicollis (Brown-headed tamarin) | His | Full L. Full Length (1-316) |
|
| RFL16275PF | Recombinant Full Length Puma Yagouaroundi Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Puma yagouaroundi (Jaguarundi) (Herpailurus yagouaroundi) | His | Full L. Full Length (1-317) |
|
| RFL16665OF | Recombinant Full Length Sheep Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Sheep | His | Full L. Full Length (1-317) |
|
| RFL16912PF | Recombinant Full Length Pongo Pygmaeus Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Pongo Pygmaeus | His | Full L. Full Length (1-317) |
|
| RFL16940CF | Recombinant Full Length Cercopithecus Mitis Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Cercopithecus mitis (Blue monkey) | His | Full L. Full Length (1-317) |
|
| RFL17645LF | Recombinant Full Length Leontopithecus Chrysomelas Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Leontopithecus chrysomelas (Golden-headed lion tamarin) | His | Full L. Full Length (1-310) |
|
| RFL17659SF | Recombinant Full Length Pig Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Sus scrofa (Pig) | His | Full L. Full Length (1-320) |
|
| RFL1765EF | Recombinant Full Length Horse Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Horse | His | Full L. Full Length (1-317) |
|
| RFL17719TF | Recombinant Full Length Trachypithecus Francoisi Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Trachypithecus francoisi (Francois' leaf monkey) (Presbytis francoisi) | His | Full L. Full Length (1-317) |
|
| RFL17811CF | Recombinant Full Length Capreolus Capreolus Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Capreolus capreolus (Roe deer) | His | Full L. Full Length (1-317) |
|
| RFL18232HF | Recombinant Full Length Hapalemur Griseus Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Hapalemur griseus (Gray gentle lemur) (Eastern lesser bamboo lemur) | His | Full L. Full Length (1-317) |
|
| RFL1863CF | Recombinant Full Length Callithrix Geoffroyi Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Callithrix geoffroyi (Geoffroy's marmoset) | His | Full L. Full Length (1-344) |
|
| RFL18956PF | Recombinant Full Length Pan Troglodytes Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Pan troglodytes | His | Full L. Full Length (1-317) |
|
| RFL19212EF | Recombinant Full Length Erythrocebus Patas Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Erythrocebus patas (Red guenon) (Cercopithecus patas) | His | Full L. Full Length (1-317) |
|
| RFL19774HF | Recombinant Full Length Human Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length (1-317aa ) |
|
| RFL19973SF | Recombinant Full Length Semnopithecus Entellus Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Semnopithecus entellus (Hanuman langur) (Presbytis entellus) | His | Full L. Full Length (1-317) |
|
| RFL19982MF | Recombinant Full Length Miopithecus Talapoin Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Miopithecus talapoin (Angolan talapoin) (Cercopithecus talapoin) | His | Full L. Full Length (1-317) |
|
| RFL20250CF | Recombinant Full Length Chaetodipus Baileyi Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Chaetodipus baileyi (Bailey's pocket mouse) (Perognathus baileyi) | His | Full L. Full Length (1-317) |
|
| RFL20458AF | Recombinant Full Length Alouatta Pigra Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Alouatta pigra (Guatemalan howler monkey) (Mexican black howler monkey) | His | Full L. Full Length (1-317) |
|
| RFL20641AF | Recombinant Full Length Alouatta Seniculus Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Alouatta seniculus (Red howler monkey) | His | Full L. Full Length (1-317) |
|
| RFL20828TF | Recombinant Full Length Trachypithecus Cristatus Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Trachypithecus cristatus (Silvered leaf-monkey) (Presbytis cristata) | His | Full L. Full Length (1-317) |
|
| RFL21131CF | Recombinant Full Length Callimico Goeldii Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Callimico goeldii (Goeldi's marmoset) | His | Full L. Full Length (1-344) |
|
| RFL22448AF | Recombinant Full Length Allenopithecus Nigroviridis Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Allenopithecus nigroviridis (Allen's swamp monkey) | His | Full L. Full Length (1-317) |
|
| RFL22525MF | Recombinant Full Length Mammuthus Primigenius Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Mammuthus primigenius (Siberian woolly mammoth) | His | Full L. Full Length (1-317) |
|
| RFL2270CF | Recombinant Full Length Colobus Guereza Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Colobus guereza (Mantled guereza) (Eastern black-and-white colobus monkey) | His | Full L. Full Length (1-317) |
|
| RFL23245PF | Recombinant Full Length Presbytis Comata Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Presbytis comata (Grizzled leaf monkey) | His | Full L. Full Length (1-317) |
|
| RFL23282SF | Recombinant Full Length Saguinus Imperator Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Saguinus imperator (Emperor tamarin) | His | Full L. Full Length (1-317) |
|
| RFL23397CF | Recombinant Full Length Dog Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Dog | His | Full L. Full Length (1-317) |
|
| RFL23573LF | Recombinant Full Length Loris Tardigradus Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Loris tardigradus (Slender loris) | His | Full L. Full Length (1-317) |
|
| RFL24495CF | Recombinant Full Length Goat Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Goat | His | Full L. Full Length (1-317) |
|
| RFL24596RF | Recombinant Full Length Rangifer Tarandus Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Rangifer tarandus (Reindeer) (Cervus tarandus) | His | Full L. Full Length (1-317) |
|
| RFL24833SF | Recombinant Full Length Saguinus Oedipus Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Saguinus oedipus (Cotton-top tamarin) | His | Full L. Full Length (1-317) |
|
| RFL25188LF | Recombinant Full Length Leontopithecus Chrysopygus Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Leontopithecus chrysopygus (Golden-rumped lion tamarin) (Leontopithecus rosalia chrysopygus) | His | Full L. Full Length (1-318) |
|
| RFL25732DF | Recombinant Full Length Dama Dama Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Dama dama (Fallow deer) (Cervus dama) | His | Full L. Full Length (1-317) |
|
| RFL26092VF | Recombinant Full Length Varecia Variegata Rubra Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Varecia variegata rubra (Red ruffed lemur) (Varecia rubra) | His | Full L. Full Length (1-317) |
|
| RFL27339VF | Recombinant Full Length Varecia Variegata Variegata Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Varecia variegata variegata (Black and white ruffed lemur) | His | Full L. Full Length (1-317) |
|
| RFL28065LF | Recombinant Full Length Lemur Catta Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Lemur catta (Ring-tailed lemur) | His | Full L. Full Length (1-317) |
|
| RFL29288AF | Recombinant Full Length Alces Alces Alces Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Alces alces alces (European moose) (Elk) | His | Full L. Full Length (1-317) |
|
| RFL29405VF | Recombinant Full Length Vulpes Lagopus Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Vulpes lagopus (Arctic fox) (Alopex lagopus) | His | Full L. Full Length (1-317) |
|
| RFL30418CF | Recombinant Full Length Cebuella Pygmaea Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Callithrix pygmaea (Pygmy marmoset) (Cebuella pygmaea) | His | Full L. Full Length (1-344) |
|
| RFL30884CF | Recombinant Full Length Callithrix Jacchus Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Callithrix jacchus (White-tufted-ear marmoset) | His | Full L. Full Length (1-344) |
|
| RFL30979OF | Recombinant Full Length Ovibos Moschatus Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Ovibos moschatus (Muskox) | His | Full L. Full Length (1-317) |
|
| RFL31045HF | Recombinant Full Length Hylobates Lar Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Hylobates lar (Common gibbon) (White-handed gibbon) | His | Full L. Full Length (1-317) |
|
| RFL3134GF | Recombinant Full Length Chicken Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Chicken | His | Full L. Full Length (1-314) |
|
| RFL3158GF | Recombinant Full Length Galago Senegalensis Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Galago senegalensis (Northern lesser bushbaby) (Senegal bushbaby) | His | Full L. Full Length (1-317) |
|
| RFL31716AF | Recombinant Full Length Ateles Paniscus Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Ateles paniscus (Black spider monkey) (Red-faced black spider monkey) | His | Full L. Full Length (1-317) |
|
| RFL31770BF | Recombinant Full Length Bovine Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Bovine | His | Full L. Full Length (1-317) |
|
| RFL31862PF | Recombinant Full Length Papio Hamadryas Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Papio hamadryas (Hamadryas baboon) | His | Full L. Full Length (1-317) |
|
| RFL32738CF | Recombinant Full Length Callithrix Argentata Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Callithrix argentata (Silvery marmoset) (Mico argentatus) | His | Full L. Full Length (1-344) |
|
| RFL32755CF | Recombinant Full Length Cebus Albifrons Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Cebus albifrons (White-fronted capuchin) | His | Full L. Full Length (1-316) |
|
| RFL34363NF | Recombinant Full Length Nomascus Concolor Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Nomascus concolor (Black crested gibbon) (Hylobates concolor) | His | Full L. Full Length (1-317) |
|
| RFL34928CF | Recombinant Full Length Chaetodipus Penicillatus Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Chaetodipus penicillatus (Desert pocket mouse) (Perognathus penicillatus) | His | Full L. Full Length (1-317) |
|
| RFL36034AF | Recombinant Full Length Alouatta Palliata Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Alouatta palliata (Mantled howler monkey) | His | Full L. Full Length (1-317) |
|
| RFL36130SF | Recombinant Full Length Saguinus Midas Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Saguinus midas (Midas tamarin) (Golden-handed tamarin) | His | Full L. Full Length (1-317) |
|
| RFL36275SF | Recombinant Full Length Saimiri Oerstedii Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Saimiri oerstedii (Central American squirrel monkey) | His | Full L. Full Length (1-317) |
|
| RFL36441CF | Recombinant Full Length Chlorocebus Aethiops Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Chlorocebus Aethiops | His | Full L. Full Length (1-317) |
|
| RFL3748CF | Recombinant Full Length Cercopithecus Diana Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Cercopithecus diana (Diana monkey) | His | Full L. Full Length (1-317) |
|
| RFL4535TF | Recombinant Full Length Trachypithecus Obscurus Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Trachypithecus obscurus (Dusky leaf-monkey) (Presbytis obscura) | His | Full L. Full Length (1-317) |
|
| RFL4558AF | Recombinant Full Length Alouatta Sara Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Alouatta sara (Bolivian red howler monkey) | His | Full L. Full Length (1-317) |
|
| RFL5087MF | Recombinant Full Length Macaca Silenus Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Macaca silenus (Lion-tailed macaque) | His | Full L. Full Length (1-317) |
|
| RFL5188GF | Recombinant Full Length Gorilla Gorilla Gorilla Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Gorilla gorilla gorilla (Western lowland gorilla) | His | Full L. Full Length (1-316) |
|
| RFL5631MF | Recombinant Full Length Mouse Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Mus musculus | His | Full L. Full Length (1-315) |
|
| RFL6739AF | Recombinant Full Length Alouatta Caraya Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Alouatta caraya (Black howler monkey) | His | Full L. Full Length (1-317) |
|
| RFL6831PF | Recombinant Full Length Papio Anubis Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Papio anubis (Olive baboon) | His | Full L. Full Length (1-317) |
|
| RFL7457MF | Recombinant Full Length Macaca Nigra Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Macaca nigra (Celebes black macaque) (Crested black macaque) | His | Full L. Full Length (1-317) |
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| RFL8537HF | Recombinant Full Length Hylobates Muelleri Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Hylobates muelleri (Mueller's Bornean gibbon) | His | Full L. Full Length (1-317) |
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| RFL9520SF | Recombinant Full Length Saguinus Geoffroyi Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Saguinus geoffroyi (Geoffroy's tamarin) | His | Full L. Full Length (1-316) |
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| RFL956MF | Recombinant Full Length Macaca Nemestrina Melanocyte-Stimulating Hormone Receptor(Mc1R) Protein, His-Tagged | E.coli expression system | Macaca nemestrina (Pig-tailed macaque) | His | Full L. Full Length (1-317) |
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Involved Pathway
MC1R involved in several pathways and played different roles in them. We selected most pathways MC1R participated on our site, such as Neuroactive ligand-receptor interaction,Melanogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with MC1R were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Neuroactive ligand-receptor interaction | PTH1RB,LTB4R2,HRH4,PRL2,CHRNA6,CHRNA5,HCRTR1,CHRNB3A,AVPR1A,GRM6 |
| Melanogenesis | WNT11B,HRAS,CALM,EDNRBA,LEF1,WNT2B,Adcy4,FZD3,GNAI1,WNT11R |
Protein Function
MC1R has several biochemical functions, for example, G-protein coupled peptide receptor activity,hormone binding,melanocortin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MC1R itself. We selected most functions MC1R had, and list some proteins which have the same functions with MC1R. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| hormone binding | LRP2,CALR,UCN2,CRYM,NPR1,ADIPOR1A,TTR,ADIPOR2,NPR2,ADIPOR1B |
| melanocyte-stimulating hormone receptor activity | MC3R,MC4R |
| ubiquitin protein ligase binding | CCDC50,STX8,ERLIN2,CUL2,SMAD6,PRR5L,MID1,PRKACA,CXCR4,PER3 |
| G-protein coupled peptide receptor activity | RXFP3,CYSLTR1,GPR37L1,NPR3,CYSLTR2,NPR1,RXFP3.2B,GRPR,RXFP4,LTB4R2 |
| melanocortin receptor activity | MC5R,MC2R,MC4R,MC5RB,MC5RA,MC3R |
| protein binding | FAT4,CLPB,POP7,DNER,HSPA14,C9orf100,KRT81,MEF2A,UNC13A,SAC3D1 |
Interacting Protein
MC1R has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MC1R here. Most of them are supplied by our site. Hope this information will be useful for your research of MC1R.
MRAP;MRAP2
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References
- Duarte, CW; Stohn, JP; et al. Elevated Plasma Levels of the Pituitary Hormone Cthrc1 in Individuals with Red Hair but Not in Patients with Solid Tumors. PLOS ONE 9:-(2014).
- Spichty, R; Balimann, M; et al. A bioassay for the detection of neutralizing antibodies against the alpha-melanocyte stimulating hormone analog afamelanotide in patients with erythropoietic protoporphyria. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 75:192-198(2013).
