LMNB1
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Official Full Name
lamin B1 -
Overview
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. -
Synonyms
LMNB1;lamin B1;lamin-B1
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Chicken
- Mouse
- Zebrafish
- E.coli
- Mammalian Cell
- HEK293
- Wheat Germ
- HEK293T
- Mammalian cells
- In Vitro Cell Free System
- Mamanlian cells
- His
- Myc&DDK
- Non
- His&Fc&Avi
- Flag
- GST
Involved Pathway
LMNB1 involved in several pathways and played different roles in them. We selected most pathways LMNB1 participated on our site, such as Apoptosis,Apoptotic cleavage of cellular proteins,Apoptotic execution phase, which may be useful for your reference. Also, other proteins which involved in the same pathway with LMNB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cellular Senescence | CDKN2B,CBX6,CBX4,MINK1,CBX6A,TERF2IP,HIST4H4,TNIK,HIST1H1E,HIST2H3C |
| Breakdown of the nuclear lamina | CASP6L2,CASP6L1 |
| Apoptotic cleavage of cellular proteins | OCLN,PLEC,DSG1,CTNNB1,DBNLB,CTNNB2,STK24,CASP8L1,GAS2,CASP6L2 |
| Apoptotic execution phase | CASP6L2,BMX,DBNLA,STK24A,PKP1,CTNNB1,DSG3,DSG2,CASP6L1,PANK1A |
| Caspase cascade in apoptosis | TFAP2A,TOP1,PARP1,NUMA1,GAS2,CRADD,DIABLO,CASP4,CFL2,ACTA1 |
| Cell cycle | TFDP2,CENPA,BARD1,ORC1L,ERCC6L,ORC2L,ANAPC7,NINL,CENPN,ORC2 |
| Apoptosis | IRF2,FASLG,TNFRSF1A,CTNNB2,CASP7,IRF4,ATM,STK24,BAXA,CASP6L2 |
| Cell Cycle, Mitotic | CENPE,CEP76,SSNA1,CDK11A,ESCO2,PANE1,MASTL,B9D2,CDKN2C,CENPI |
Protein Function
LMNB1 has several biochemical functions, for example, phospholipase binding,structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LMNB1 itself. We selected most functions LMNB1 had, and list some proteins which have the same functions with LMNB1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| structural molecule activity | CLTA,CLDN11,EVPL,LAD1,MAP7D1B,SNTA1,CLDN20,SYNM,ROCK2,EPB41L2 |
| phospholipase binding | PTPN11,CALM,DGKQ,ARHGAP6,APOC2,CALM3,PRKCZ,PDPK1,NEFL,WAS |
Interacting Protein
LMNB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LMNB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LMNB1.
LRRK2;PASK;SEPT12;RTCA;AIRE;BCAR3;ATG12;ZWINT;HLA-B;YWHAZ;Atm;PIAS2;SERPINA3;LMNA;ATF4;GIT2;y1085_fratt
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References
- Liu, H; Zhang, JL; et al. Screening of autoantibodies as potential biomarkers for hepatocellular carcinoma by using T7 phase display system. CANCER EPIDEMIOLOGY 36:82-88(2012).
- Nishida, Y; Aida, K; et al. Antibody-Validated Proteins in Inflamed Islets of Fulminant Type 1 Diabetes Profiled by Laser-Capture Microdissection Followed by Mass Spectrometry. PLOS ONE 9:-(2014).
