KMO
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Official Full Name
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) -
Overview
Kynurenine 3-monooxygenase is an enzyme that in humans is encoded by the KMO gene. -
Synonyms
KMO;kynurenine 3-monooxygenase (kynurenine 3-hydroxylase);kynurenine 3-monooxygenase;dJ317G22.1;Kynurenine 3 hydroxylase;Kynurenine 3 monooxygenase (kynurenine 3 hydroxylase);Kynurenine 3 monooxygenase;RP1-317G22.1;kynurenine 3-hydroxylase;AI046660
Recombinant Proteins
- Rat
- Zebrafish
- Human
- Mouse
- Sus scrofa (Pig)
- zebrafish
- Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
- Mus musculus
- Mammalian Cell
- HEK293
- Sf9 Insect Cell
- HEK293T
- Insect Cell
- Yeast
- E.coli
- Mammalian cells
- E. coli
- Wheat Germ
- In Vitro Cell Free System
- E.coli expression system
- His
- Myc&DDK
- Flag
- Non
- Avi&Flag
- His&Fc&Avi
- His&T7
- N-6xHis
- N-10xHis
- His&SUMO
- N-Met and 6×His
- GST
Involved Pathway
KMO involved in several pathways and played different roles in them. We selected most pathways KMO participated on our site, such as Tryptophan metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with KMO were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Tryptophan metabolism | ABP1,OGDHL,ALDH9A1B,TDO2,KYNU,ALDH7A1,HAAO,ASMT,AOX4,ALDH9A1 |
| Metabolic pathways | CYP4A12A,ST3GAL1,CKMT1B,TYRP1B,POLR2K,AKR1A1A,CMPK,PNMT,ALG5,ST8SIA5 |
Protein Function
KMO has several biochemical functions, for example, FAD binding,NAD(P)H oxidase activity,flavin adenine dinucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KMO itself. We selected most functions KMO had, and list some proteins which have the same functions with KMO. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| NAD(P)H oxidase activity | DERL3,CYB5R4,NOX4,DUOX2,AIFM1 |
| flavin adenine dinucleotide binding | AIFM4,NOS1,AOX3,SDHA,DUS1L,NOX4,AOX4,DLDH,ACOX1,ACADS |
| FAD binding | CRY2,ACOX1,PRODH,DDO,DAO.3,DAO.1,DERL3,MICAL2B,MICAL2,DAO |
Interacting Protein
KMO has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KMO here. Most of them are supplied by our site. Hope this information will be useful for your research of KMO.
Resources
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References
- KOBAYASHI, TK; YAKUSHIJI, M; et al. GASTRIC-CARCINOMA METASTATIC TO THE BONE-MARROW - IMMUNOPEROXIDASE IDENTIFICATION OF KMO-1 ANTIGEN IN MGG-DESTAINED ASPIRATE. DIAGNOSTIC CYTOPATHOLOGY 7:597-600(1991).
