KAT8

  • Official Full Name

    K(lysine) acetyltransferase 8

  • Overview

    This gene encodes a member of the MYST histone acetylase protein family. The encoded protein has a characteristic MYST domain containing an acetyl-CoA-binding site, a chromodomain typical of proteins which bind histones, and a C2HC-type zinc finger. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

  • Synonyms

    KAT8;K(lysine) acetyltransferase 8;MOF;hMOF;MYST1;ZC2HC8;histone acetyltransferase KAT8;MYST-1;lysine acetyltransferase 8;histone acetyltransferase MYST1;MYST histone acetyltransferase 1;MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1;probable histone acetyltransferase MYST1;ortholog of Drosophila males absent on the first (MOF)

Recombinant Proteins

  • Zebrafish
  • Human
  • Rat
  • Mouse
  • Mammalian Cell
  • Sf9 Insect Cell
  • E.coli
  • HEK293
  • His
  • GST
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
KAT8-12013Z Recombinant Zebrafish KAT8 Mammalian Cell Zebrafish His
KAT8-1602H Recombinant Human K(Lysine) Acetyltransferase 8, GST-tagged Sf9 Insect Cell Human GST 2-467 a.a.
KAT8-3158R Recombinant Rat KAT8 Protein Mammalian Cell Rat His
KAT8-6957H Recombinant Human KAT8 , GST-tagged Sf9 Insect Cell Human GST 2-467 aa
KAT8-8453M Recombinant Mouse KAT8 Protein Mammalian Cell Mouse His
KAT8-1162HCL Recombinant Human KAT8 cell lysate Human Non
KAT8-0524H Recombinant Human KAT8 Protein (M1-K458), Tag Free E.coli Human Non M1-K458
KAT8-2814R Recombinant Rat KAT8 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
KAT8-2814R-B Recombinant Rat KAT8 Protein Pre-coupled Magnetic Beads HEK293 Rat
KAT8-4703M Recombinant Mouse KAT8 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
KAT8-4703M-B Recombinant Mouse KAT8 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    KAT8 involved in several pathways and played different roles in them. We selected most pathways KAT8 participated on our site, such as Chromatin modifying enzymes,Chromatin organization,HATs acetylate histones, which may be useful for your reference. Also, other proteins which involved in the same pathway with KAT8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Chromatin modifying enzymes HIST2H3C,CHD4A,PBRM1,KAT6A,SUZ12B,SMARCC1B,MEAF6,SMARCC2,GATAD2AB,C3orf75
    Chromatin organization PHF20B,PAX3A,KDM4D,SMARCB1A,SAP18,PADI4,PRDM16,KDM6B,KDM5A,ARID2
    HATs acetylate histones CAPNS2,KAT7B,KAT7A,MCRS1,TADA2A,ACTL6A,VPS72,ELP4,PHF15,MSL2A
    p53 pathway NEDD8,TTC5,PPP1R13L,HUWE1,CSNK1G3,CSE1L,TRIM28,FBXO11,DYRK2,E4F1

    Protein Function

    KAT8 has several biochemical functions, for example, acetyltransferase activity,enzyme binding,histone acetyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KAT8 itself. We selected most functions KAT8 had, and list some proteins which have the same functions with KAT8. You can find most of the proteins on our site.

    Function Related Protein
    metal ion binding BMI1B,Reln,ZNF501,FAM96A,RAF1A,ZFP512,POLK,SNAI1,ZFP473,MOB3A
    acetyltransferase activity AANAT2,HHAT,MBOAT4,MBOAT1,EP300,NAT14,CREBBP,CML5,MBOAT7,CML2
    enzyme binding ESR2,CYP2A6,ZNF346,LAMB1,CYP3A4,CA,YES1,N4BP2L2,HLCS,YWHAH
    contributes_to histone acetyltransferase activity (H4-K16 specific) OGT,KANSL2,KIAA1267,PHF20B,MCRS1,KANSL3,HCFC1
    protein binding DAO,CKM,DKK1,SREK1,AP1M2,MCEE,C10orf28,KCNK16,AGTRAP,AKT2
    methylated histone binding MPHOSPH8,PHF8,L3MBTL2,RBBP5,JHDM1D,ING4,ING2,TP53BP1,MTF2,ZMYND11
    contributes_to histone acetyltransferase activity (H4-K8 specific) KANSL3,MCRS1,OGT,HCFC1,KANSL2,PHF20B,KIAA1267
    transcription factor binding HDAC3,C1QBP,PDX1,EPN1,PBX1,PPARGC1A,MED25,TRP53,TAF7L,CREBBP
    histone acetyltransferase activity NCOA3,KAT6A,HAT1,KAT7A,KAT7,TAF1,EP300,ATF2,CDYL,vnc

    Interacting Protein

    KAT8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KAT8 here. Most of them are supplied by our site. Hope this information will be useful for your research of KAT8.

    KMT2A;TP53;RNF2;WDR5;RBBP5;HHF1;HST2;Kat8;ESRRA;H2AFX;ASH2L

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