Jam2
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Official Full Name
junctional adhesion molecule 2 -
Overview
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. -
Synonyms
JAM2;junctional adhesion molecule 2;C21orf43;junctional adhesion molecule B;CD322;JAM B;JAMB;VE JAM;JAM-2;JAM-IT/VE-JAM;vascular endothelial junction-associated molecule;JAM-B;VEJAM;PRO245;VE-JAM
Recombinant Proteins
- Mouse
- Chicken
- Rhesus macaque
- Human
- Rat
- HEK293
- Mammalian Cell
- E.coli
- Human Cell
- Yeast
- Mammalian cells
- His
- Fc
- Non
- hIgG4
- His&Fc&Avi
Involved Pathway
Jam2 involved in several pathways and played different roles in them. We selected most pathways Jam2 participated on our site, such as Cell adhesion molecules (CAMs),Tight junction,Leukocyte transendothelial migration, which may be useful for your reference. Also, other proteins which involved in the same pathway with Jam2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Epithelial cell signaling in Helicobacter pylori infection | ATP6V1C2,TJP1,MAPK11,CDC42,ATP6V1G1,ATP6V1C1,LYN,CXCR2,ATP6V1G3,ATP6V0D2 |
| Cell adhesion molecules (CAMs) | CLDN7,HLA-DQA1,NLGN2,NTNG1,HLA-DQA2,NRXN1A,CD8B,NFASCA,MADCAM1,LRRC4B |
| Tight junction | MPP5A,PPP2R1A,CLDNA,MYH9,MYH7,CLDNG,MYL10,YBX3,SHROOM1,RRAS |
| Leukocyte transendothelial migration | CLDN3,CLDN7,CYBB,CYBA,CLDN15,VCAM1,RHOH,GNAI1,CD99,VAV1 |
Protein Function
Jam2 has several biochemical functions, for example, protein binding,protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Jam2 itself. We selected most functions Jam2 had, and list some proteins which have the same functions with Jam2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein heterodimerization activity | IKZF3,KCNIP1,APOA2,NEUROD1,HIST1H3F,KCNK9,TBX15,BCL2,HIST1H4C,HEYL |
| protein binding | MRPL28,DHX36,TBC1D16,PDIA2,HOMER1,KLRC4-KLRK1,SNW1,ORM1,CALB1,SOX7 |
Interacting Protein
Jam2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Jam2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Jam2.
PARD3;JAM3;TDP2;SOX8;YBX1;NME3;Pick1;CSNK1A1L;GPR20
Resources
Research Area
Immunoglobulin Superfamily CAMsEpithelial Cell Markers and Intracellular Molecules
Tight Junctions
Related Services
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References
