HOXB13
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Official Full Name
homeobox B13 -
Overview
This gene encodes a transcription factor that belongs to the homeobox gene family. Genes of this family are highly conserved among vertebrates and essential for vertebrate embryonic development. This gene has been implicated to play a role in fetal skin development and cutaneous regeneration. In mice, a similar gene was shown to exhibit temporal and spatial colinearity in the main body axis of the embryo, but was not expressed in the secondary axes, which suggests functions in body patterning along the axis. This gene and other HOXB genes form a gene cluster at chromosome the 17q21-22 region. [provided by RefSeq, Jul 2008] -
Synonyms
HOXB13;homeobox B13;PSGD;homeobox protein Hox-B13
Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
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HOXB13-2425H | Recombinant human HOXB13, His-tagged | E.coli | Human | His |
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HOXB13-4903H | Recombinant Human HOXB13 protein, GST-tagged | Wheat Germ | Human | GST | 1-284 a.a. |
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HOXB13-336HCL | Recombinant Human HOXB13 lysate | HEK293 | Human | Non |
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HOXB13-41H | Recombinant Human HOXB13 Protein, His-tagged | E.coli | Human | His |
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HOXB13-644HF | Recombinant Full Length Human HOXB13 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 284 amino acids |
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Involved Pathway
HOXB13 involved in several pathways and played different roles in them. We selected most pathways HOXB13 participated on our site, such as Regulation of Androgen receptor activity, which may be useful for your reference. Also, other proteins which involved in the same pathway with HOXB13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Regulation of Androgen receptor activity | NR0B1,TRIM24,KAT7,NR2C2,SRY,APPBP2,SMARCE1,SMARCA2,SPDEF,GATA2 |
Protein Function
HOXB13 has several biochemical functions, for example, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HOXB13 itself. We selected most functions HOXB13 had, and list some proteins which have the same functions with HOXB13. You can find most of the proteins on our site.
Function | Related Protein |
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sequence-specific DNA binding | FOXD1L,NR5A5,NR1H5,FOXN4,TA,NKX1.2LA,PHOX2BB,ZBTB33,PBX1A,ZGPAT |
Interacting Protein
HOXB13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HOXB13 here. Most of them are supplied by our site. Hope this information will be useful for your research of HOXB13.
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